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12y ago
  • The process takes place in rough endoplasmic reticulum is
  • Lysosomal enzymes with a mannose-6-phosphate marker added in the cis-Golgi network
  • Secreted proteins, either secreted constitutively with no tag or secreted in a regulatory manner involving clathrin and paired basic amino acids in the signal peptide.
  • Integral membrane proteins that stay embedded in the membrane as vesicles exit and bind to new membranes. Rab proteins are key in targeting the membrane; SNAP and SNARE proteins are key in the fusion event.
  • Initial glycosylation as assembly continues. This is N-linked (O-linking occurs in the golgi).
    • N-linked glycosylation: If the protein is properly folded, glycosyltransferase recognizes the AA sequence NXS or NXT (with the S/T residue phosphorylated) and adds a 14-sugar backbone (2-N-acetylglucosamine, 9-branching mannose, and 3-glucose at the end) to the side-chain nitrogen of Asn.
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13y ago

The smooth endoplasmic reticulum of the small intestine make lipids from fatty acids and glycerol (lipid synthesis), this is then passed onto the Golgi apparatus for export.

The smooth endoplasmic reticulum can also make steriods.

Rough endoplasmic reticulum is concerned with the transport of proteins which are made by the ribosomes on its surface.

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15y ago

the reaction of a cell that transports items

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12y ago

organelle in which components of the cell membrane are assembled and some proteins are modified

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8y ago

The rough endoplasmic reticulum is similar to an assembly line in a factory making proteins.

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13y ago

proteins

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Q: What process takes place in the rough endoplasmic recticulum?
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Related questions

How is rough endoplasmic recticulum different from smooth endoplasmic recticulum?

rough endoplasmic reticulum (RER) has ribosomes attached to it but SER doesn't


Hepatocytes have large amounts of what?

smooth endoplasmic recticulum


What is the function of rough endoplasmic recticulum in a cell?

help in protein synthesis ,,


How can you tell from rough endoplasmic- recticulum from smooth endoplasmic reticulum?

Rough ER has ribosomes. Smooth ER lack those


What is the rough endoplasmic recticulum job?

to make sure no chemical can get to the nucleas of the cell.


Which cell organelle produces new membrane for the cell?

The endoplasmic reticulum is responsible for the manufacturing of membranes. It also creates ribosomes that make proteins for the cell.


Where is the rough endoplasmic recticulum in the cell?

The RER is a rather large organelle and it is next to the nuclear membrane and the cellular membrane.


What is endoplasmic recticulum do?

The rough ER modifies proteins and ships them to the Golgi apparatus. The smooth ER is involved in lipid manufacturing.


What is the rough endoplasmic recticulum function?

The rough ER folds and processes proteins. It is a vital part of protein synthesis and also has numerous ribosomes attached to it/ near it.


What does endoplasmic recticulum do in a animal cell?

It's function is to make proteins. The RER has ribosomes embedded in its' membrane and that is what produces its' rough appearance.


What is a series of folded membranes that move materials around the cell?

Endoplsmic Recticulum. There are two types of ER. The rough and smooth ER. The rough ER is dotted with ribosomes.


Which of these organelles is coverd in ribosomes?

The rough endoplasmic reticulum is covered in ribosomes. In fact, it is called 'rough' because of the presence of ribosomes which give it a rough looking appearance. Technically, the rough endoplasmic reticulum is actually the region of the greater 'endoplasmic reticulum' where protein synthesis takes place. Another region of the endoplasmic reticulum is the 'smooth endoplasmic reticulum' where lipids are synthesized and other metabolic functions take place. The quantity of rough versus smooth endoplasmic reticulum is somewhat in flux and varies based on the needs of the cell.