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The Mississippi river.

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Q: What river system drains the middle of the US?
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Related questions

What river system drains most of the central part of the US?

the Missouri river


What is the river system which drains much of the water to the east of the Rockies in the US?

Mississippi River


What river that drains the interior of the US?

The Mississippi River.


What huge river that drains the central region of the US?

The Mississippi river


What river drains most of the central part of the US?

the Missouri river


What river drains the interior of US?

Mississippi


What large river drains the central US?

The Mississippi River, being fed by the Ohio River and Colorado River.


What river drains the entire Interior Plains and is the longest river in North America?

The Missouri River is longer, but may be considered a tributary to the Mississippi River, which drains much of the eastern interior of the US.


What is the name of the largest basin in north America?

The Mississippi-Missouri river system. This includes the Ohio river. It drains the whole of the US East of the Rocky mountains & west of the Appalatians.


River that drains the interior of the US?

The Mississippi River, and its tributaries including the Missouri and Ohio Rivers. The Missouri River can be considered to be the longest interior river.


What US river does not flow into the Atlantic nor the Pacific?

== == The Mississippi River drains into the Gulf of Mexico. Did you also know that the Mississippi River is the second longest river in The United States, only to the Missouri?


What river drains almost half of the US and serves as a transportation route between the upper and Midwest and the gulf coast?

The Mississippi.