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As the wound heals , during the second stagefibroblasts grow and form an ECM (extracellular matrix) . This ECM is formed by excreting collagen and fibronectin.

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Q: What tissue-forming cell is involved in wound healing?
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Without macrophages why is wound healing is delayed?

Without macrophages, wound healing is greatly delayed. Macrophages are cells that dispose of bad or dead tissue and help clean the wound.


Is the healing of a wound an example of mitosis?

Yes in the sense that the new growth of cells the covers/mends the wound. But the growth of new cells by mitosis doesn't necessarily "heal" - there are a variety of factors in the healing process.


Role of cell division in wound healing?

Cell division via mitosis is the way the body grows and replaces cells. If you have a wound you need to make new cells to replace the dead/injured ones as well as fill in any holes or gaps that may be in evidence.


Which kind of reproduction replaces dead cells and is involved with healing?

The replacement of dead cell in any living body is generally done by the cell division technique. Mitosis cell division is the most basic cell division which reproduces cells in place of dead cells. This type of cell division also involves with healing.


What are the function of platelets?

Platelets play a fundamental role in hemostasis, i.e. keeping blood inside the blood vessel. The opposite of hemostasis is hemorrhaging - bleeding. In simple terms, platelets help form blood clots to stop bleeding. They are also a natural source of growth factors - specifically platelet derived growth factor (PDGF) and transforming growth factor Beta (TGFß), both of which are contained within the alpha granules of platelets. In response to platelet to platelet aggregation or platelet to connective tissue contact, as occurs in injury or surgery, the cell membrane of the platelet is "activated" to release these alpha granules. The alpha granules release these growth factors via active extrusion through the cell membrane. These growth factors are involved with initiating wound healing. PDGF's main functions are to stimulate cell replication (mitogenesis) of healing capable stem cells and what are also called pre-mitotic partially differentiated osteoprogenitor cells which are also part of the connective tissue-bone healing cellular composite. It also stimulates cell replication of endothelial cells. This will cause budding of new capillaries into the wound (angiogenesis), a fundamental part of all wound healing. In addition, PDGF seems to promote the migration of perivascular healing capable cells into a wound and to modulate the effects of other growth factors. Cells which are activated by TGFß1 or TGFß2 include fibroblasts, endothelial cells, osteoprogenitor cells, chondroprogenitor cells, and mesenchymal stem cells. If a fibroblast is "activated" it will undergo cell division and produce collagen. An endothelial cell will be stimulated to produce new capillaries. An osteoprogenitor cell will further differentiate and produce bone matrix. A chondroprogenitor cells will further differentiate and produce the matrix for cartilage. A mesenchymal stem cell will be stimulated to mitose so as to provide the large population of wound healing cells needed for completion of healing.


Does cell growth increase as the wound heals?

yes .. Cell growth increase as wound heals, bec. the cells are multiplying to form a new tissues and the new skin to replace the wound ;)))


What can be some of the results of poor cell signaling in the human body?

There are several deleterious results of poor cell signalling in the human body. If cells cannot signal, immune function may be compromised. The subject could be more prone to illness, and wound healing could be compromised.


What is the name of the cell that causes the wound to clot when you cut your self?

the red blood cell


What is the function fibroblasts?

A fibroblast is a type of cell that synthesizes the extracellular matrix and collagen, the structural framework (stroma) for animal tissues, and plays a critical role in wound healing. Fibroblasts are the most common cells of connective tissue in animals.


Why do you need zinc?

Zinc is needed in the immune system. It also plays a role in cell division and growth, wound healing, and the breakdown of carbohydrates. Zinc is necessary in order to smell and taste as well.


What has the author Shailendra K Saxena written?

Shailendra K. Saxena has written: 'Intestinal regeneration' -- subject(s): Cell division, Cytology, Growth, Growth & development, Intestinal Mucosa, Intestines, Physiology, Regeneration, Regeneration (Biology), Wound healing


Which organ secretes the hormone for Red blood cell formation?

Erythropoietin, or its alternatives erythropoetin or erithropoyetin or EPO, is a glycoprotein hormone that controls erythropoiesis, or red blood cell production. It is a cytokine for erythrocyte (red blood cell) precursors in the bone marrow.Also called hematopoietin or hemopoietin, it is produced by the peritubular capillary endothelial cells in the kidney and liver, it is the hormone that regulates red blood cell production. It also has other known biological functions. For example, erythropoietin plays an important role in the brain's response to neuronal injury. EPO is also involved in the wound healing process