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What type of ion channel opening is caused by the binding of neurotransmitters to the receptors on the motor endplate?
Wiki User
∙ 9y ago
Sodium enters the cell and causes depolarization. A small amount of potassium also leaves the motor end plate. This means binding of the neurotransmitter causes chemically gated sodium channels to open in the motor end plate.
calcium
Wiki User
∙ 9y ago
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How does neurotransmitters initiate depolarization?
Let's picture a presynaptic neuron, a synaptic cleft, and a postsynaptic neuron. An action potential reaches the terminal of a presynaptic neurone and triggers an opening of Ca ions enters into the depolarized terminal. This influx of Ca ions causes the presynaptic vesicles to fuse with the presynaptic membrane. This releases the neurotransmitters into the synaptic cleft. The neurotransmitters diffuse through the synaptic cleft and bind to specific postsynaptic membrane receptors. This binding changes the receptors into a ion channel that allows cations like Na to enter into the postsynaptic neuron. As Na enters the postsynaptic membrane, it begins to depolarize and an action potential is generated.
What role does neurotransmitters play in neurotransmission?
In between 2 neurones is the synaptic cleft, the gap between the pre and post-synapse. NTs are the molecules which activate receptors on the post-synapse during synaptic transmission, The activated receptors initiate intracellular mechanisms such as ion channel opening, G-protein activation, etc, which can inhibit or produce action potentials (nerve impulses).
What is a channel linked receptor?
A channel linked receptor transduces functions of the same protein molecule. An example of a channel linked receptor are neurotransmitters in the brain.
What water-soluble hormone would most likely bind to what membrane proteins?
Channel linked receptors bind to neurotransmitters. (also called ion channels and ligand gated ion channels) A ligand is the signal molecule i.e the neurotransmitter. Hormones bind to intracellular receptors because hormones are non polar and can cross the cell's plasma membrane. (also called cytoplasmic receptors)
What are the cell surface receptorss?
G-protein, ion-channel and enzyme-linked protein receptors.
A “ligand-gated” ion channel is one that will open in response to:?
A specific molecule binding to it
What is ligand gated ion channel?
Ionotropic receptors are ligand-gated or transmitter gated ion channels. The binding of a neurotransmitter or other ligand to a particular site on a domain of a protein in the receptor causes a conformational change in the protein subunits. This allows a certain ion to pass through, poteitally potassium, sodium or chloride. There are two types of ionotropic receptors, non-NMDA and NMDA. Both are ligand gated receptors, however the NMDA is also voltage gated.
Ion channel gates close the pore of some ions channels in response to what?
Streching of the cell membrane, a change in electrical charge, and the binding of specific molecules to the channel.
Are all taste buds equal receptors to all different primary tastes?
yes, taste can be sensed all around the mouth... Salty spicy and sour are ion channel modulated- so EVERY cell in the mouth can allay that taste the rest are all G protein coupled receptor based- and also most cells have this..
Are receptors and enzymes both located in the cell membrane?
Yes. There are many proteins embedded in the phospholipid bilayer. Some of these proteins are enzymes, and some are receptors; the receptors are glycoproteins, with short chains (oligosaccharides) of sugar residues attached to the protein. Other proteins act as means of transporting atoms, ions, and molecules across membranes (channel and carrier proteins).
How do you compare conventional distribution channels with the vertical marketing system?
Under the conventional distribution arrangement a channel member negotiates deals with others that do not result in binding relationships. But, under the vertical arrangement a channel member feels tied to one or more members of the distribution channel.
Binding of a signaling molecule to which type of receptor leads directly to a change in the distribution of ions on opposite sides of the membrane?
Ligand-gated ion channel
