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The type of mutation that causes a defect in the gene (causing sickle cell anaemia) is a substitution mutation.

A single nucleotide substitution (A to T) in the β-globin gene causes the amino acid valine to replace glutamic acid. This changes the resulting protein, causing a haemoglobin with an abnormal shape to be created.

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11y ago
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12y ago

Substitution causes sickle cell anemia.

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Q: What type of mutation causes sickle cell anemia substitution deletion insertion mutagen?
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Related questions

What are types of point mutation?

The types of point mutations are: base-pair substitution, insertions, deletions, and frameshift mutations. In base-pair substitution, one nucleotide and its corresponding partner are replaced with another pair of nucleotide. In insertion, nucleotide pairs are added to a gene. In deletion, nucleotide pairs are taken out of a gene. Frameshift mutation happens as a result of insertion or deletion when more or less than three (or a multiple of three) nucleotide pairs are added to or taken from a gene.


Is mutagen an environmental factor that causes mutation?

It increases the odds of mutation.


What is physicial or chemical agents known as that can cause mutagen?

a change in the mRNA makes a mutation of the DNA


How can you use the mutation and mutagen in the same sentence?

by sucking your weener


Mutations that change one or just a few of nucleotides in a gene on a chromosome are called what?

the correct answer is C. a substitution i know this cause i have this book to this question and point mutation is not one of the answer and i found the answer in the book -No its substituton you jack wagon your books wrong


What is the Difference between a mutant and mutation?

A mutagen is a substance that CAUSES a mutation. Essentially, mutagens are the cause, mutations are the effect. Simple as that :)


What type of mutation occurs in reproductive cells and can be passed to offspring?

Sex cells


Why are revertants observed in Ames test?

To determine whether whatever chemical that was introduced to the bacteria is a mutagen. More revertants means better mutagen ie. the probability of a strain reverting back to wild-type is high since probability of a mutation in the DNA is high due to induced mutation by the mutagen. Less revertants means poor mutagen ie. the probability of a strain reverting back to wild-type is low since probability of a mutation in the DNA is attributed to just the probability of an error in replication.


Any agent which causes a change in DNA is a mutagen?

these are all mutagenic agents:-ultraviolet radiation from sunlight -free radicals that are formed as by-products of aerobic respiration -aflatoxins that are found in moldy grains


Which of the these would most likely cause a mutation?

A mutagen is a substance that has the potential to cause a mutation in the DNA.


What is a gene mutation?

Gene mutation is the change in the DNA sequence that is permanent and leads to new genetic traits and even diseases. This type of mutation is triggered through hereditary process or through several factors in the environment.


What is a mutagen?

an environmental angent that changes DNA. APEX