As a genral rule, highways with even numbers, run East to West while Highways with odd numbrs run from North to South. While there are a few diagonal highways that do not fit the rules, and by-pass roads around major cities that would confuse Henry the Navigator, the system seems to be fairly effective.
All odd numbered highways run North/South. All even numbered highways run East/West.
Interstate highways
East to West. Even number highways run E/W. Odd number highways run N/S
There are many highways throughout California. Interstate 5 and 80 are the major highways in the state. Both highways run through the capital of Sacramento.
I-90 and I-94 are east-west interstate highways in Montana.
East and West
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I-90 and I-94 are east-west interstate highways in Montana.
The United States Interstate Highway System was designed so that even-numbered routes are east-west highways.
The Federal Government funded 90% of the National System of Interstate Defense Highways.
Maryland has a few major highways in it. Interstate 95 is one of the busiest highways in the country. It runs north and south. Also 70 and 83 run through the state.