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Yellow fever, known historically as yellow jack, yellow plague, or bronze john, is an acute viral disease causing jaundice (caused by liver damage) if the person goes into a secondary stage. There is a vaccine. In the 18th and 19th centuries, yellow fever was seen as one of the most dangerous Infectious Diseases. The overall fatality rate for the disease 3%. In severe epidemics, the mortality may exceed 50%. But with vaccines, the rates are much less.
The problem is that the countries that this occurs in are very poor and the cost of vaccination is high.
Yellow fever virus is found in tropical and subtropical areas in South America and Africa. The virus is transmitted to humans by the bite of an infected mosquito.

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