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It's probably a bad Powertrain Control Module (Main Computer). This is a note from one of my previous posts;

Have you noticed the odometer display saying NO BU5? This actually means "no Bus", a communication term for a data route. It is saying that the dashboard sub-computer is not communicating with the main computer (PCM) which is located on the passenger side of the engine compartment, bolted just above the wheel well area. Check the 3 connectors to see if they are plugged in all the way. If they are, your PCM is probably bad (mine lasted 90k miles). This is something you can't replace yourself because the new one must be programmed with the mileage and VIN and other info by MOPAR before it's installed. Be careful, because when the PCM fails, your money pit (Durango) will start to suddenly stall at the worst times (Freeway, Boat launch, stop light on a one lane road) and not restart until you disconnect the battery for 10 minutes and then reconnect.

Good luck! The dealer charged me $800 to replace mine. $500 for the part and $300 to diagnose the problem. And I told them it was a bad PCM when I brought it in.

P.S. Even if it's not giving the odometer indication, suspect the PCM. I didn't notice the "NO BU5" indication right away when the thing would kill on the highway.

UPDATE: PCM's are now available on ebay, and they can be programmed by the seller. You'll save lots of money over the dealer.

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Q: What will cause 99 durango engine stop running while driving?
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