You should monitor the renal functions because amphotericin B is known to cause nephrotoxicity (lower incidence with lipid formulations). The patient's glomerular will show an increased BUN (Blood Urea Nitrogen) and increased serum creatinine; the tubular will show K+ (potassium ion) and/or Mg2+ (magnesium ion) wasting. To manage the patient's condition better, 0.5-1 L normal saline should be given 30-60 min prior to every dose of amphotericin B, and electrolytes should be supplemented. Other things to watch out are phlebitis, anemia, lipid formulations may cause a pulmonary reaction, and liposomal formulations may cause hyperbilirubinemia. In addition, look out for drug interactions which include other nephrotoxins (e.g. aminoglycosides, vancomycin, cyclosporine). Amphotericin are also incompatible with many IV solutions since they have the risk of precipitation.
Amphotericin B.
Fungizone
Amphotericin B
treatment begins with Amphotericin B (Fungizone / MYCOTRIN ), sometimes in combination with 5-flucytosine (Ancobon/Ancotil/CYTOFLU). Amphotericin B is a powerful fungistatic drug with potentially toxic side effects if not monitored properly instead use Amphotericin B Liposomal (MYCOLIP) to keep it Easy.
Yes
Amphotericin B.We can combine this Amphotericin B with Flucystosine or Fluconazole to get a synergistic effect.
Amphotericin B
No, vancomycin is usually given for Gram-positive bacterial infections and aspergillosis is caused by fungal disease. These fungal diseases are best treated with antibiotics like amphotericin-B .
An antibiotic used to treat mucormycosis and other severe fungal infections.
amphotericin b
B
as its deadly if it enters blood stream. it may couse Hemeolysis or a Clot