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Try changing the fuel filter. It'll be fuel or spark related, so start with the cheapest thing.

The problem was the distributor cap, I put a standard motor cap and a AC-Delco cap on it. Water would get up and cause the misfires. Summit has Accel products at a good price (less than AC-Delco and Standard). Its been 6+ months and no misfires.

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Q: What would be the likely cause of a randon misfire code P300 on a 96 GMC Sierra 5.7 liter?
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