during prophase, in order to allow microtubules to attach to the duplicated chromosomes
the nuclear envelope breaks down during prophase near the same time the chromatin condenses.
If the nuclear envelope didn't break down, the spindle would not attach to the kinetochore proteins on the condensed chromosomes in prometaphase because the nuclear envelope would be in the way.
The base pairs in DNA are broken apart during replication. Specific enzymes such as DNA polymerase break the nucleic acids apart forming two chains of DNA.
Replication.
DNA helicases break the hydrogen bonds in the DNA molecule
During the interphase
In mitosis the nuclear envelope begins to break in prophase. In meiosis the nuclear envelope begins to break in prophase 1.
the nuclear envelope breaks down during prophase near the same time the chromatin condenses.
If the nuclear envelope didn't break down, the spindle would not attach to the kinetochore proteins on the condensed chromosomes in prometaphase because the nuclear envelope would be in the way.
To be or not to be, that is the question.
Answerlate prophase (aka prometaphase)
So that the DNA can replicate/duplicate.
"...the nuclear envelope and the nucleolus break up, dispersing, and are no longer visible..." (Hole's essentials of human anatomy & physiology, 67).
The nuclear membrane breaks down during prophase, while the Deoxyribonucleic Acid (DNA) The nuclear membrane must break down to allow the chromosomes to be pulled apart and away from the area of the former nucleus towards the pole where the daughter cell will be formed. If the nuclear membrane did not break down the spindle fibers would not be able to reach the chromosomes and they would not be moved towards opposite poles of the cell.
The base pairs in DNA are broken apart during replication. Specific enzymes such as DNA polymerase break the nucleic acids apart forming two chains of DNA.
Replication.
It stops.