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While Juan Ponce de León is given credit for discovering and naming La Florida ("the land of flowers") in 1513, he is also remembered for his failure to establish Spain's first North America colony in 1521 near present day Tampa Bay. His party was attacked and Juan Ponce was killed by local Calusa natives. In 1526 La Florida Governor Lucas Vásquez de Ayllón established the first Spanish colony, San Miguel de Gualdape, on South Carolina's coast but disease, starvation and a bitter winter forced its few survivors to return to Santo Domingo. Ayllón's replacement as governor of La Florida, Pánfilo de Narváez, sailed from Spain for Hispaniola ["Mother of America"] with a fleet of five vessels and 600 soldiers to conquer the Gulf Coast near Pensacola. He too failed and others thereafter (including Hernando de Soto) until Supreme Commander Pedro Menéndez founded St. Augustine in 1565 (the oldest city in USA), routed French Huguenots at Fort Caroline and founded San Mateo (near Jacksonville, FL). Menéndez established his capital for La Florida at Santa Elena [Parris Island, SC] and ordered Captain Juan Pardo to marched northward (following De Soto's path) into the Carolinas and eastern Tennessee, building forts 1567-1568 along the way to claim this land for King Phillip II. This adventure also failed and Spain retreated into Florida and the Gulf Coast thus allowing England to arrive on the Atlantic coast.

[Source: Clark, Spanish Attempts to Colonize Southeast North America: 1513-1587]

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The Spanish first settled on the northeast coast region of the Florida peninsula.

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Florida was acquired from Spain in 1819

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Spanish Florida ended in 1819.

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Q: When did the spanish colonize in Florida?
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