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When is a mutation harmful?

Updated: 8/9/2023
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13y ago

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Not all mutations are harmful. A mutation the give the organism antibiotic resistance, for example, is quite helpful. A different mutation that causes a necessary protein to misfold may result in death. In general mutations that affect proteins that are necessary for life will result in the death of the organism. One such mutation is in the protein p53 which is necessary to prevent a cell from growing uncontrollable (cancer). A mutation in p53 could result in a cell with damaged DNA to reproduce - this is what we call cancer.

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15y ago
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13y ago

Mutations that would disrupt, remove etc. genetic coding for proteins that are essential for life.

For example, if the sequence that coded for insulin were changed or altered in any way which resulted in the gene not being able to produce insulin anymore, then you would not be able to produce insulin and the mutation would be considered harmful.

Not all mutations are harmful. There are also beneficial and neutral mutations in which the coding could be bettered or unaffected respectively.

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10y ago

Some are harmful because the result of the decoding ends with cells and proteins that don't work. For example sickle cell anemia.There is just one mutation in the very large protein hemoglobin which carries oxygen. In SE, this doesn't work right and the body cells do not get the oxygen they need for growth.

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11y ago

Genetic mutations are not always harmful. A lot of mutations have a positive effect on the host. Some genetic mutations may help the host endure certain conditions in the environment, or eat certain food, or resist a certain superbug or virus, etc etc. However, some mutations can be harmful. Sometimes our little enzymes workers make mistakes and it can cause a "harmful" genetic mutation, such as a third leg or arm, or a third nipple. It really depends on what kind of genetic mutation it is to know if it's bad or good, and a lot of mutations are not harmful, they are just unnecessary and give no benefit to the host nor do they harm the host.

Got this information from my head from last semesters Microbiology course.

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10y ago

Not all mutations are harmful. Some are beneficial. Harmful ones make it harder for an organism to live in their environment. For example a clam without a shell. But some mutations give some an edge. For example a clam with a slightly harder shell.

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13y ago

it can turn evil on you and do gruesome stuff

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13y ago

One way mutations can be harmful is that they might make you susceptible to a certain kind of disease you are already immune to.

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13y ago

Always, a mutation leads to cancer.

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