Saint Rose of Lima was the first saint from the Americas to be canonized,The first person born in the Americas to be canonized as a saint was St. Rose of Lima. The first person born in the United States to be canonized as a saint was St. Elizabeth Ann Seton.
She was canonized September 14, 1975, by Pope Paul VI.
St. Elizabeth of Hungary.
Elizabeth was canonized on May 27, 1235, by Pope Gregory IX at Perugia, Italy. This was just a few years after the Church institued the new canonization process so we do not have a date for her beatificatiion, if there was one.
Elizabeth was canonized on September 14, 1985, by Pope John Paul II.
St. Frances Cabrini was the first US citizen to be canonized. St. Elizabeth Ann Seton was the first person born in the US to be canonized. (Mother Cabrini was an Italian immigrant.)
St. Francis Xavier was canonized with fellow missionary St. Ignatius in 1622.
St. Eligius was canonized in the Pre-Congregation era. This was when people were often canonized because of their popularity while they were alive.
St. Etheldreda was canonized by Pope Celestine III in 1198.
The truth be told, St. Frances Xavier Cabrini was the first American citizen to be canonized. Elizabeth Ann Seton was the first American born saint to be canonized. Technically, St. Rose of Lima is the first American saint. She was born and lived in Lima, Peru. Peru is part of the Americas.
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St. Anselm was canonized in 1494.