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What has the author Kenneth Maiese written?
Kenneth Maiese has written: 'Forkhead transcription factors' -- subject(s): Forkhead transcription factors, Forkhead Transcription Factors, Physiology
What can inhibit transcription by blocking the binding of positively acting transcription factors to the DNA?
The binding of negatively acting transcription factors, chromatin remodeling complexes, DNA methylation, or histone deacetylation can inhibit transcription by preventing the binding of positively acting transcription factors to the DNA.
What is the study of transcription called?
The study of transcription is called transcriptional regulation. It involves understanding how genes are transcribed into RNA molecules, which can then be translated into proteins. Researchers study factors that influence transcription, such as transcription factors, promoters, and enhancers.
How can we distinguish between general and specific transcription factors in gene regulation processes?
General transcription factors are involved in the basic transcription process, while specific transcription factors regulate the expression of specific genes. One way to distinguish between them is by looking at their binding sites on DNA: general transcription factors bind to the core promoter region, while specific transcription factors bind to enhancer or silencer regions near the gene they regulate.
Do transcription factors bind to enhancers to regulate gene expression?
Yes, transcription factors bind to enhancers to regulate gene expression by controlling the rate of transcription of specific genes.
What is the difference between sigma factors and transcription factors in gene regulation?
Sigma factors are specific proteins in prokaryotes that help RNA polymerase bind to the promoter region of a gene to initiate transcription. Transcription factors, on the other hand, are proteins in eukaryotes that regulate gene expression by binding to specific DNA sequences and influencing the activity of RNA polymerase. In summary, sigma factors are specific to prokaryotes and help initiate transcription, while transcription factors are found in eukaryotes and regulate gene expression.
What is the role of transcription factors in regulating gene expression by binding to enhancers?
Transcription factors are proteins that control the activity of genes by binding to enhancers, which are specific DNA sequences that enhance gene expression. By binding to enhancers, transcription factors can either activate or repress the transcription of genes, thereby regulating gene expression.
What specific sequences do transcription factors bind to on DNA?
Transcription factors bind to specific DNA sequences called enhancers and promoters to regulate gene expression.
What does Transcription in eukaryotes require in addition to RNA polymerase?
Transcription in eukaryotes requires additional transcription factors, which are proteins that help RNA polymerase recognize the promoter region of a gene, initiate transcription, and regulate gene expression. These transcription factors are essential for the accurate and efficient transcription of genes in eukaryotic cells.
Which is true of transcription factors?
They control which genes are expressed.
What kind of organisms use transcription factors?
Eukaryotes
What Transcription factors bind directly to DNA and affect whether and how fast a gene is transcribed?
Transcription factors that bind directly to DNA are classified as either activators or repressors. Activators enhance gene transcription by binding to specific enhancer regions, facilitating the recruitment of RNA polymerase, while repressors inhibit transcription by binding to silencer regions or blocking the assembly of the transcriptional machinery. Examples of key transcription factors include the TATA-binding protein (TBP), which is part of the transcription factor complex that initiates transcription, and various specific transcription factors like NF-kB and MyoD that regulate genes in response to specific signals. Their interactions with promoter and enhancer regions ultimately determine the rate of transcription for target genes.
