mitochondria
Oxidative deamination typically takes place in the liver, specifically within hepatocytes. This process involves the removal of an amino group from an amino acid, resulting in the production of ammonia and a keto acid.
The process of deamination removes the amino group from an amino acid. The amino part of the amino acid is converted into urea carried by the blood into the kidneys and removed as urine. In human body deamination takes place primarily in the liver, however, glutamate is also deaminated in the kidneys.
Deamination...... (:
Deamination primarily occurs in the liver, although it can also occur in the kidneys and intestine. Enzymes such as amino acid oxidases and dehydrogenases are involved in the process of removing amino groups from amino acids to produce ammonia.
Deamination is the process by which an amino group is removed from a molecule.
Amino acid deamination primarily occurs through two processes: oxidative deamination and non-oxidative deamination. In oxidative deamination, amino acids are converted into their corresponding α-keto acids by the action of enzymes like glutamate dehydrogenase, releasing ammonia and reducing equivalents. Non-oxidative deamination, on the other hand, involves the direct removal of an amino group without oxidation, often mediated by enzymes such as amino acid racemases or aminotransferases. Both processes play crucial roles in amino acid catabolism and nitrogen metabolism.
Deamination is the removal of an amino group and its value to a microbe is that it allows the amino acid to be used as a carbon and energy source.
deamination, the removal of the amino group from an amino acid. This is often accomplished by transamination. The amino group is transferred from an amino acid to an -keto acid acceptor. The organic acid resulting from deamination can be converted to pyruvate, acetyl-CoA, or a TCA cycle intermediate and eventually oxidized in the TCA cycle to release energy. It also can be used as a source of carbon for the synthesis of cell constituents. Excess nitrogen from deamination may be excreted as ammonium ion, thus making the medium alkaline.
Deamination and decarboxylation reactions are both types of organic transformations in which a functional group is removed from a molecule. Deamination involves the removal of an amino group (-NH2), while decarboxylation involves the removal of a carboxyl group (-COOH). Both reactions are important in various metabolic pathways in living organisms.
Deamination
There are two products: a keto acid and ammonia
Oxidative deamination is started in the liver as part of the Krebs cycle process. This produces ammonia which must be secreted from the body as urea and urine.