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deamination, the removal

of the amino group from an amino acid. This is often accomplished

by transamination. The amino group is transferred from

an amino acid to an -keto acid acceptor. The organic

acid resulting from deamination can be converted to pyruvate,

acetyl-CoA, or a TCA cycle intermediate and eventually oxidized

in the TCA cycle to release energy. It also can be used as a

source of carbon for the synthesis of cell constituents. Excess nitrogen

from deamination may be excreted as ammonium ion, thus

making the medium alkaline.

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