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Creatine is synthesized in the liver and kidneys. The first step of synthesis is the reaction between two amino acids known as Arginine (C6H14N4O2) and Glycine (NH2CH2COOH) in the kidneys. The reaction is catalyzed by L-Arginine:glycine amidinotransferase (AGAT). It is important to note that creatine is the feedback inhibitor of AGAT. The resulting reaction produces the by-product Ornithine (C5H12N2O2) which according to animal research increases muscle growth by stimulating the release of anabolic hormones such as growth hormone and insulin. The reaction also produces guanidinoacetic acid which is catalyzed by the enzyme GAMT (S-adenosyl-L-methionine:N-guanidinoacetate methyltransferase) to form creatine in the liver. Creatine is then transported to the skeletal muscles through the bloodstream. Creatine is then converted to phosphocreatine through the addition of a phosphate group by an ATP molecule. This conversion is catalyzed by the enzyme creatine kinase. Creatine phosphate is stored in the muscle for immediate use.
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If you eat more creatine what happens to the amount synthesized by your body?
It increases
Does creatine affect the birth control pill?
No. Creatine is naturally produced in your body.
Can all fatty acids be synthesized in the body?
No, not all fatty acids can be synthesized by the body. The body is not capable of synthesizing polyunsaturated or trans fatty acids.
What is Creatine Ethyl Ester?
Creatine Ethyl Ester is a newer, slightly more expensive form of the popular supplement creatine. Creatine is most commonly sold in the form of creatine monohydrate. Creatine ethyl ester is, essentially, a modified form of creatine monohydrate that has been "esterified." This means that an ethyl ester compound has been attached to the creatine, which theoretically makes it more efficiently absorbed by the body.
What is a dispensable amino acid?
Can be synthesized by the body.
Vitamins and minerals cannot be what in our body?
"synthesized"
Can niacin be synthesized in the body?
yes from tryptophan
Can you take creatine with water pills?
You can mix creatine with diet pills. It would not hurt anything or cause any negative side effects. Creatine provides energy to the muscles in your body.
What does creatine have to do with creatine?
Creatine is creatine. However, if you mean creatinine and creatine, they are two different things. Creatinine is created when the body breaks down creatine, and is a waste product. It is eliminated through the kidneys and into the urine. Creatinine in large amounts can cause kidney damage and can kill you, or put you into a dialysis machine for some time. However, this is usually caused when a large amount
What role does creatine play in the develpoment of lean muscle mass?
Creatine occurs naturally in the body and is an amino acid. Studies on the effect of creatine on the acquisition of lean muscle mass give mixed results though and the general consensus is that creatine can sometimes help with this, but not always.
Is it true that your body will quit producing it's own form of Creatine if you take too much supplemental Creatine?
Yes This is precisely why they tell you to cycle creatine so your body won't lose too much of its own creatine producing abilities. Just stay within your limits and forget about that loading phase and you should be fine. Of course, you could always just choose to not take any creatine. It is not as crucial as you would think.
Does creatine have testosterone it?
Creatine does not have any hormones in it. It simply adds to your store of energy in the muscles (it basically adds a phosphate to be used as ATP). You eat creatine in meat every day, and your body makes some as well.
