Fragile X is a result of a mutation in the FMR1 gene on the X chromosome.
No, Fragile X is on the X chromosome. Females have 2 X chromosomes and Males have an X and a Y Chromosome. Therefore, both males and females can have Fragile X (they can have the full mutation or be carriers). Males are usually more severly affected because they have only one X Chromosome.
Fragile X syndrome is caused by a mutation that prevents the Fragile X mental retardation (Fmr-1) gene from being transcribed. This gene is located on the X chromosome (the sex chromosome). Since males only carry one of these chromosomes, they are twice as likely to be affected by the mutation than females.
Yes. It is found as a mutation on the X chromosome (a sex chromosome) so it is sex linked. The gene for Fragile X is carried on the X chromosome. Because both males (XY) and females (XX) have at least one X chromosome, both can pass on the mutated gene to their children.
The fragile X syndrome is a genetic disorder caused by mutation of the FMR1 gene on the X chromosome.
males have only one copy of the X chromosome. Males who inherit the full mutation are expected to have mental impairment. A female's normal X chromosome may compensate for her chromosome with the fragile X gene mutation
Fragile X Syndrome
Fragile X Syndrome
Fragile X Syndrome
Fragile X Syndrome
Fragile X Syndrome
No, Klinefelter is due to an extra chromosome, Fragile X is due to the FMR1 gene being turned off and producing no FMR1 protein
Fragile x syndrome was first described in 1943 by J.Purdon Martin and Julia Bell whose family had eleven members with fragile x symptoms although they did not know the cause or have a name for the condition at this time. In 1969, Fragile x was first discovered under the microscope by a scientist called Herbert Lubs who discovered that one of the arms of the X chromosome in people with fragile x was constricted which gave it the appearance of being broken which is how the name 'fragile x' came about. In 1991 Verkerk identified the cause for transcriptional silencing of the gene Fmr-1, that encodes the protein FMRP.