South
Florida is nearest south America in distance
There are two continents where Spanish is predominantly spoken: Europe, specifically in Spain, and South America.
You'd be headed nowhere. Since the South Pole is in Antarctica, you wouldn't have to move at all.
Someone from South America would come from the continent South America. There are two continents by the name America, north America and south America.
It would be logical; that you would be going North.
North
Northeast
you would cross mexico to get to south america.
From the south pole itself everywhere is north
In no particular order: Southern California, New Mexixo, Arizona, South Texas, South Florida, New York City, Chicago.
South-South-East