pyruvate carboxylase and phosphoenolpyruvate carboxykinase (PEPCK)
Yes, Mg2+ is a cofactor for the enzymes phosphofructo kinase-1, phosphoglycerate kinase, enolase, and pyruvate kinase in glycolysis.
Glucokinase, phosphofructokinase-1, pyruvate kinase
Hexokinase
In humans, pyruvate cannot be directly converted into glucose through a process called gluconeogenesis. This is because humans lack the specific enzymes required to convert pyruvate into glucose. Pyruvate can be converted into lactate or acetyl-CoA, which can then enter various metabolic pathways in the body.
Pyruvate enters the Krebs cycle via an intermediate called acetyl CoA.Pyruvate is formed in the cytoplasm as the end product of glycolysis. Pyruvate enters a mitochondrion, in the matrix of which it encounters the enzyme pyruvate dehydrogenase. This enzyme catalyzes the reaction of pyruvate with coenzyme A to form acetyl CoA. This reaction is sometimes called the link reaction, as it links glycolysis to the Krebs cycle (= citric acid cycle, or tricarboxylic acid cycle)."Pyruvate dehydrogenase" is in fact a huge complex (bigger than a ribosome) consisting of three enzymes and a number of other substances, including coenzymes. In the course of the reaction NAD+ is reduced to NADH. A molecule of CO2 is also produced. So this reaction involves a both an oxidation and a decarboxylation.Acetyl CoA then reacts with oxaloacetate to form citrate. Both oxaloacetate and citrate are intermediates of the Krebs cycle.
Substrates are the products of enzyme activity when metabolism occurs. For example: with glycolysis hydrogen is a substrate that is carried to the electron transport chain by NAD and FAD which then become NADH and FADH with the added hydrogen. I am just a student though, i was looking for the same answer. Just know what is produced as a result of a particular reaction and you will have your substrates. Shane
There are 1000's of enzymes in the body. In a biochemical pathway there maybe be multiple enzymes used! for examply, glycolysis..
There are very many enzymes involved. A few from glycolysis are: hexokinase and glucokinase, phosphohexose isomerase, phosphofructokinase, pyruvate kinase; from pyruvate decarboxylation are pyruvate dehydrogenase phosphatase and pyruvate dehydrogenase kinase; and a few from the Kreb's cycle are: aconitase, alpha-ketoglutamate dehydrogenase, succinate thiokinase, and fumarase.
The reaction for breaking down Glucose is called: GlycolysisThese are biological reactions. They are catalyzed by enzymes. Kinases, dehydrogenases and isomerases are important enzymes in Glycolysis.
this is shamefully vague question. In glycolysis, glucose and (hexokinase, phosphogluco-mutase, aldolase, triose-phosphate isomerase, glyceraldehyde-phosphate dehydrogenase, phosphoglycerate-kinase, phosphoglycerate mutase, enolase and pyruvate kinase) enzymes are used.
The steps in glycolysis that are irreversible are catalyzed by the enzymes hexokinase/glucokinase, phosphofructokinase, and pyruvate kinase. These steps are key regulatory points in glycolysis ensuring the forward flow of glucose through the pathway.
The ATP is molecules are generated during glycolysis in the last reaction of the pathway i.e. with the conversion of phospho enol pyruvate (PEP) to pyruvate by the enzyme pyruvate kinase. Kinases are enzymes that are capable of phosphorylating a substrate. In this case, ADP molecules are phosphorylated to generate ATP molecules In glycolysis, for every molecule of glucose that enters the pathway, two molecules of pyruvate are generated. Therefore, two molecules of ATP are generated with every glycolytic reaction.