The furthest city in England is Norwich. However the further eastly point in England is Ness Point, Lowestoft.
Great Yarmouth. But strictly speaking, it's a town and not a city.
Newcastle
Truro.
Aberdeen is furthest north.
Jerusalem
Gisborn
Karachi
dunnoman
Gisborne.
bristol
Moscow
Bern Switzerland
No. Reno NV is in the west.
Ozette, Washington is the westernmost city in the continental US.
Possibly the Antipodes Islands off the south east coast of New Zealand.