Pyruvate dehydrogenase complex react with pyruvate to form acetyl-CoA
Mitochondria
alpha-ketoglutarate dehydrogenase is most similar to pyruvate dehydrogenase as both are enzyme complexes made of 3 units
There are very many enzymes involved. A few from glycolysis are: hexokinase and glucokinase, phosphohexose isomerase, phosphofructokinase, pyruvate kinase; from pyruvate decarboxylation are pyruvate dehydrogenase phosphatase and pyruvate dehydrogenase kinase; and a few from the Kreb's cycle are: aconitase, alpha-ketoglutamate dehydrogenase, succinate thiokinase, and fumarase.
in cyptoplasm of the prokaryotic cell
Pyruvate decarboxylation -> Acetaldehyde reduction The product is ethanol. Pyruvate decarboxylation is performed by pyruvate decarxylase with cofactor thiamine pyrophosphate, and the product, acetaldehyde, is reduced by NADH. (Pyruvate decarboxylase is NOT the same as the pyruvate dehydrogenase complex in cellular respiration. Though pyruvate dehydrogenase also decarboxylates pyruvate, but the decarboxlated species immediately reacts with CoA to form acetyl-CoA).
Pyruvate dehydrogenase
Mitochondria
dehydrogenase is an enzyme which transfers hydrogen ions from a substrate to an activator.Example are activators are NAD+ and FAD+.
alpha-ketoglutarate dehydrogenase is most similar to pyruvate dehydrogenase as both are enzyme complexes made of 3 units
There are very many enzymes involved. A few from glycolysis are: hexokinase and glucokinase, phosphohexose isomerase, phosphofructokinase, pyruvate kinase; from pyruvate decarboxylation are pyruvate dehydrogenase phosphatase and pyruvate dehydrogenase kinase; and a few from the Kreb's cycle are: aconitase, alpha-ketoglutamate dehydrogenase, succinate thiokinase, and fumarase.
in cyptoplasm of the prokaryotic cell
Pyruvate dehydrogenase complex
Correct answer: I, II, III and IV
Thiamin, niacin, and riboflavin
Thiamine pyrophosphate (TPP)
Pyruvate decarboxylation -> Acetaldehyde reduction The product is ethanol. Pyruvate decarboxylation is performed by pyruvate decarxylase with cofactor thiamine pyrophosphate, and the product, acetaldehyde, is reduced by NADH. (Pyruvate decarboxylase is NOT the same as the pyruvate dehydrogenase complex in cellular respiration. Though pyruvate dehydrogenase also decarboxylates pyruvate, but the decarboxlated species immediately reacts with CoA to form acetyl-CoA).
It is carried by specific transporters (the negative charge on pyruvate won't allow it to diffuse) before being acted on by pyruvate dehydrogenase. I don't think these transports are named.