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permeability
permeabiity
permeability
permeabiity
permeabiity
permeability
They must either be lipid soluble (e.g. steroids) or very small (e.g. ions).
mass
Lipid solubility determines if it will diffuse across. The presence of specific protein carrier molecules determines if it will be transported across the membrane.
The speed doesn't necessarily determine the permeability, but the size does. Smaller molecules such as O2 can easily enter the cell while CO2 leaves the cell. There are other criteria that also determines whether a molecule can pass through the plasma membrane such as its solubility. Fat soluble molecules such as steroids can easily pass through the membrane.
Whether molecules are able to pass through the membrane depends on the size of the molecules. Smaller ones can, and larger ones cannot. Glucose can pass through a cell membrane because it is a monomer, which is a smaller molecule than the polymer molecules of starch.
One factor is the channel of the molecule, without them the ions and polar molecules would not be able to pass across. Another factor is the size of the molecule, they determine how fast it will defuse.