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When the malaria parasite is transferred to the blood from a mosquito bite what organ does the parasite first infect?
A female Anopheles mosquito carrying the malaria-causing parasites bites a human and injects the parasites in the form of sporozoites into the bloodstream. The sporozoites travel to the liver and then invade the liver cells. These mature into schizonts, which rupture and release merozoites. This form of the malaria parasite invades red blood cells.
How does mosquito spread malaria?
Malaria is actually caused by tiny parasites that live inside the mosquitoes, not by the mosquitoes themselves. Plasmodium falciparum, Plasmodium vivax, and Plasmodium ovale are the 3 most common causes of malaria. (All three are commonly called "malarial parasites"--they are closely related species.)When a mosquito first bites a human, it injects some anticoagulants to keep the blood from clotting. If the mosquito happens to be infected with a malarial parasite, the parasite will be injected with the anticoagulants and will then infect the human red blood cells.
Why does the malaria parasite spread to the liver first?
The malaria parasite, specifically Plasmodium, spreads to the liver first because it requires a safe environment to mature and multiply. After being injected into the bloodstream by an infected mosquito, the parasites enter liver cells where they undergo asexual reproduction, forming thousands of merozoites. This initial liver phase allows the parasite to evade the host's immune response and establish a significant population before entering the bloodstream and infecting red blood cells, leading to the symptomatic phase of malaria.
What two places in the human body must the malaria parasite go in oder to reproduce?
First is liver and second is red blood cells. It will be interesting to know that the parasite frequently changes the liver cells, before settling in finally.
Why plasmodium first attack on liver cells?
Plasmodium, the parasite responsible for malaria, first attacks liver cells because this is the stage of its lifecycle where it undergoes asexual reproduction. After being transmitted to humans through mosquito bites, the parasite travels to the liver, where it can multiply rapidly and form thousands of merozoites. This initial infection in the liver allows the parasite to evade the host's immune response, as liver cells provide a sheltered environment for replication before releasing the merozoites into the bloodstream, leading to the symptoms of malaria.
Why a person having malarial parasite does not shows symptoms of disease?
Some peoples (ie tribes/families) who have lived in malaria infested regions have developed a natural partial immunity to the parasite (by a process of natural selection and evolution) such people may be infected by the parasite but do not develop full blown malaria because their immune system keeps the parasite in check.Note, the danger in this is that such people act as the source of malaria affecting others. The mosquito has to bite someone with malaria FIRST then go on to bite a SECOND person. This gives malaria to the SECOND person. Obviously people carrying the malaria parasite but not ill do not go and get treated for malaria (have the parasite in their bodies killed). They therefore act as a hidden reservoir for infection.
What did the first viruses do?
Infect cells.
How the parasites of malaria avoid the host's defenses?
Malaria is a difficult infection for the human body to identify and deal with The parasite has two distinct phases - in the first, it reproduces inside the liver (it gets here within minutes after a mosquito bites you - and can stay here for 8-30 days, depending on the strain) Once they burst out of the liver cells, they go into the blood, and infect the red blood cells (second phase, here they again replicate and infect more cells) It is hard for the body to recognise in the liver, because the body does not really look 'inside' the liver cells as much. Within the red blood cells, again, it is hidden from a lot of the immune system, and needs to be destroyed in your spleen. (Althought the parasite tries to avoid this by causing your blood to clot, and avoid going to the spleen). It's important if you have symptoms of fever, and you've stayed in an area with malaria recently, to get checked - it's easily diagnosable! Also, prevention if you're thinking of travelling is cheap and effective.
How malaria first started?
-Unknown- Malaria has been infecting humans for at least 50,000 years, and may have existed as a pathogen in other species for even longer. For this reason it is impossible to know where the first cases of malaria appeared. While the earliest references to a malaria-like illness come from China, that is by no means an indication that malaria originated in Asia.
Which part of the body does the malaria effect and how?
Malaria affects the liver and the red blood cells mainly.The parasite replicates in the liver cells and in the red cells, when enough new parasites have developed the cells burst.Malaria can also affect the kidneys and brain by blocking the blood supply to these organs, when the cells of the liver and red blood cells burst.
Who proposed the name malaria?
1740 - H. Walpole first used "mal'aria" (Italian: bad air) to describe the disease 20th century - shortened to "malaria" 1880 - C. Laveran first identified the parasite in human blood 1889 - R. Ross discovered that mosquitoes transmitted malaria
Does malaria come out of your body after it's in your body?
the parasite stays inside the body but can give you no problems for 20 or 30 yrs and then just hit you like when you first had it
