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Dementia
The disorder characterized by a slowly progressive decline in mental abilities is Alzheimer's disease. It is a neurodegenerative condition that primarily affects memory, thinking, and behavior. As the disease progresses, individuals may experience difficulty with daily tasks, language problems, and changes in mood and personality.
Chlamydia is progressive.
Osteoporosis
macular degeneration
A progressive condition, usually beginning in adulthood.
Progressive pneumonia is a condition in which pneumonia isn't adequately treated, and has relapsed into a heavier pneumonia, which tends to be harder to treat.
In the personality it does not necessarily interfere with your life it is just who you are, the disorder is a chronic condition that cripples you.
primary sclerosing cholangitis (progressive liver disease)
You bet! Acne is a temporary condition. A good personality is forever.
Hansen's disease
dissociative identity disorder