Undersecretion of TH during fetal development or infancy cause cretinism, a condition characterized by dwarfism and delayed mental and sexual development.
The hormone whose production is inadequate in myxedema is thyroid hormone, specifically thyroxine (T4). Myxedema is a severe form of hypothyroidism, which occurs when the thyroid gland does not produce enough thyroid hormone. This leads to a variety of symptoms, including fatigue, weight gain, cold intolerance, and dry skin.
In the book "Human Physiology: From Cells to Systems, Fourth Edition," Lauralee Sherwood writes that this autoimmune disease causes the body to overproduce thyroid-stimulating immunoglobulin (TSI), an antibody that targets the thyroid-stimulating hormone (TSH).
An underactive thyroid occurs with the thyroid doesn't produce enough thyroid hormones. This is most commonly referred to as hypothyroidism. An underactive thyroid also occurs due to Hashimoto's thyroiditis (a thyroid autoimmune condition) as well as postpartum thyrioditis. Thyroid conditions are hereditary in nature, especially among women.
thyroid hormone release is stimulated by thyroid stimulating hormone,which is released by adenohypophysis of pituitary gland .this in turn stimulated by thyroid releasing factor which is released by hypothalamus .in the presence of this thyroid stimulating hormone conversion of inactive iodine to active iodine takes place.and also formation of T3 and T4 hormones occurs under the influence of this hormone only, this reaction is favored by this hormone.it stimulates thyroid gland to release thyroid hormone which is composed of T3 and T4 units.T is nothing but the tyrosine units present in throglobulin a colloid present in lumen of thyroid follicles.
Hyperplasia of the Thyroid gland occurs as a result of dyshormonogenic goiter, endemic goiter, Graves' disease, or due to multinodular goiter.
The thyroid is a butterfly shaped gland located in the neck, behind the larynx. The whole body is affected by the hormones secreted by the thyroid gland; therefore it is difficult if not impossible to say that the thyroid has an effect on one organ, more than another. The hormones produced by the thyroid regulate most of the body's organs; the pituitary gland regulates and monitors the amount of the thyroid's hormone levels; telling it what to product, release and store. Too much thyroid hormone, as well as too little, can have an effect upon the body and how it functions. So when the thyroid is functioning well, the whole body is well; but as a thyroid problem develops the body can become ill, and in some cases even die.If the thyroid functions as it should, it regulates the rate of the body's metabolism, the rate of growth, body weight, body temperature, skeletal and muscle strength, heart-rate, breathing, blood pressure, cholesterol levels, brain development, nervous system, concentration, energy level, immune system, condition of tissues, skin and hair. Another primary function of the thyroid is the conversion of iodine into hormones that are used throughout the body, these are thyroxine and triiodothyronine; and if the thyroid is functioning well, it inhibits the production of thyrotropin and thyrotropin which can have a negative effect on the body's organs.There are several thyroid hormone disorders/diseases, some of these are Graves disease (those most affected are 30-50), Autoimmune thyroid syndrome/condition (affecting mostly women), Hashimoto's thyroiditis (one of the autoimmune disorders), Papillary thyroid cancer (most common type of thyroid cancer, and readily spreads to other organs), general Thyroid Endocrine cancer (occurs most often after 40 and is one of the most common endocrine cancers), (Addison's disease - there is a connection between the thyroid pathology and some individuals with Addison's disease), Thyroid Nodules (middle aged women are most effect and most nodules are non-cancerous), Thyroid Eye disease (found most in smokers with thyroid disorders/diseases, including those with Graves disease), Hyperthyroidism (called "overactive thyroid," the thyroid makes excessive hormones), Myxedema Hypothyroidism (can result in coma, even death)…
Hyperthyroidism occurs when the thyroid gland produces too much thyroid hormone. Hyperthyroidism can cause several complications, including heart complications. Another name for hyperthyroidism is Thyrotoxicosis
Typically a jittery feeling, or trembling hands, is a symptom of hyperthyroidism. Hyperthyroidism occurs when the thyroid produces too much thyroid hormones. To make sure you are taking the proper dose of thyroid medication talk with your doctor and ask them to check your thyroid hormone levels.
Hyperthyroidism is a disorder that occurs when the thyroid gland makes more thyroid hormone than the body needs. Hyperthyroidism is tied to family history and heredity, so it's rare to contract it independent of those factors.
There are several causes of hyperthyroidism. Most often, the entire gland is overproducing thyroid hormone. Less commonly, a single nodule is responsible for the excess hormone secretion, called a "hot" nodule
When a drop in the level of hormones in the body occurs, it causes a chain reaction of responses. It is called negativefeedback because it causes system output to oppose system input, rather than support it.Example: Thyroxine (a thyroid hormone) level in the blood drops. The hypothalamus then sends out an order for TSH (thyroid stimulating hormone) to the anterior pituitary gland. The pituitary releases the TSH. TSH then causes the thyroid to start producing thyroxine again. When the blood level rises, the hypothalamus stops producing TSH, causing the thyroid to stop producing thyroxine. This happens in a loop until stabilization occurs.
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