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5-fluorouracil,
gentamicin,
cisplatin,
acetaminophen,
para-aminophenol,
potassium dichromate,
doxorubicin,
cyclosporine,
citrinin,
puromycin
Acyclovir
Aminoglycosides
Cisplatin
Mercury Chloride
Potassium Bromate
Cadmium chloride
Amphotericin B
Lithium
Calcineurin Inhibitors
amongst others
Wiki User
∙ 13y ago
Wiki User
∙ 11y agoMany drugs cause liver toxicity.
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What drug causes liver tumors?
antidepresants
What is the drug that causes liver kidney and lung damage?
any drug
Are drugs with low therapeutic index more effective?
Not necessarily. Simply put, a low TI indicates that the dose that causes a beneficial effect is "close" to the dose that causes unacceptable toxicity or lethality. A drug with a large or wide TI means that the dose that causes the beneficial effect is far lower than the dose that causes toxicity or lethality. If a drug has a TI of 2, then the drug dose that causes toxicity is twice that which causes the benefit. So a mistake of taking 2 pills instead of 1 can be disastrous. If a drug has a therapeutic index of 13, then the dose expected to cause toxicity is 13x that which causes the toxic effects, and is pretty safe. To compare effectiveness of a drug, you have to compare drug efficacy and TI. For a large TI drug, sometimes you just need to increase the dose. In the example above where TI=13, you could increase the dose 6 0r 7 times and you may not see an increase in toxic effects.
Dose of a test drug that causes death in the animal during short term toxicity testing is referred to as the?
A: Lethal Dose
What is the toxicity of ganciclovir?
The toxicity profile of this drug when administered systemically includes granulocytopenia, anemia and thrombocytopenia. The drug is in pregnancy category C
The dose of a test drug that causes death in the animal during short term toxicity testing is referred to?
A: Lethal Dose
What causes cirrhosis of liver?
The worst drug available- alcohol. There are others, but alcohol is the most common.
What causes cirrhosis of the liver?
The worst drug available- alcohol. There are others, but alcohol is the most common.
What is the difference between a drug-drug interaction and drug disease?
drug-drug interaction is when two or more drugs interact pharmacodynamically in such a way that the toxicity of one or more drugs are altered.while drug desease is any negative feedback a drug come with like addiction, tolerance, dependency. examples of drug deseases are veral hepatitis, drug abuse, drug induced liver desease e.t.c.
What is selective toxicity?
Selective toxicity is the ability of a chemical or drug to kill a microorganism without harming its host.
Why chloramphenicol causes gray baby syndrome?
Chloramphenicol is metabolized by the liver. A baby's liver is not mature enough to metabolize this drug. Therefore the levels of Chloramphenicol increase in the baby's body, as there is no way for the baby to get rid of the drug. This causes cardiovascular collapse (severe hypotension), cyanosis, flaccidity, and vomiting.
What causes durg-induced hepatitis?
Drug-induced hepatitis (also called toxic hepatitis) occurs in eight in every 10,000 people because the liver reacts abnormally during drug exposure, leading to liver damage.
