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The event that occurs first in appositional growth of bones is cells of inner layer of periosteum differentiate into osteoblasts.
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∙ 10y ago
The first event in appositional growth of bones is the activation of osteogenic cells, also known as osteoblasts. These cells become active in response to various factors such as hormones or mechanical stress. Once activated, osteoblasts start depositing new bone matrix on the outer surface of existing bone, leading to an increase in bone thickness.
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