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Charcot-Marie-Tooth disease is actually a heterogenous group of disorders known to be caused by variants on 40 genes. The most common form of CMT is caused by a duplication on chromosome 17 that results in an extra copy of the gene for Peripheral Myelin Protein 22 or PMP22. This duplication causes demyelination of the nerve axons, and, eventually, muscular atrophy. For more, visit www.charcot-marie-tooth.org.

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15y ago
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13y ago

Chromosome 15 is the one carrying the genes for the enzyme hexosaminidase A, which is deficient in Tay-Sachs Disease.

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13y ago

it is found on either chromosome 13 or 7

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Q: Which genes are responsible for Charcot-Marie-Tooth?
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