Blood glucose levels in the pre-diabetesrange increase the risk of heart attack or stroke by 50%
While the exact cause of diabetes has not been completely identified yet there is evidence that both hereditary and environmental are factors. Both of them may help in the development of prediabetes and insulin resistance.
Insulin resistance is caused by obesity and a family history of insulin resistance. You can develop insulin resistance without these, but it's rare. Insulin resistance leads to type 2 diabetes. A type 1 diabetic can develop insulin resistance the same way anyone else does, but becoming obese and by having insulin resistance in the family. In this case, the insulin resistance and the type 1 diabetes are totally unrelated.
Insulin resistance may be stimulated by elevated concentrations of fatty acids and triglycerides. Specific cells secrete the insulin in response to elevated blood amino acid concentrations.
Diabetes Mellitus
Genetic factors contributing to insulin resistance cannot be changed as of the early 2000s.
No, borderline diabetes is termed prediabetes or impaired glucose tolerance. It indicates that your body, for whatever reason (most commonly insulin resistance or inadequate secretion of insulin) has elevated levels of glucose that does not qualify as "diabetic" levels. This may progress to diabetes in time, or the glucose levels may return to normal.
A normal level would be below 140 mg/dL, 140 to 199 mg/dL it is impaired glucose tolerance or prediabetes, 200 mg/dL is a diagnosis of diabetes, 2 hours after the glucose drink.
High blood sugar from food stimulates the pancreas to secrete insulin into the blood. However, in insulin resistance, the insulin is secreted but is only partially absorbed by the tissues.
In its mildest form, insulin resistance causes no symptoms, and is only recognizable on laboratory tests.
obesity increases insulin resistance and thereby reduces the effectiveness of insulin.
Insulin resistance.
Retinol binding protein, TNF alpha, Interleukin, Chimerin are some. Some can reduce insulin resistance- Adiponectin