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The dancer, choreographer, and director Gower Champion died of WM the night his last show, "42nd Street," opened on Broadway.
The playwright Jack Gelber ("The Connection") was president of the NYC WM support group until his death.
The Nobel Prize-winning physicist Richard Feynman, Algerian president Houari Boumedienne, and French president and prime minister Georges Pompidou all died of WM.
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How prevalent is Waldenstrom's macroglobulinemia?
It is estimated that it may affect about five out of every 100,000 people
How can you find out what famous people have been diagnosed with schizophrenia?
One can find a list of famous people that have been diagnosed with schizophrenia on the 'schizophrenia dot com' website. There is also a similar list on Wikipedia.
Are there any famous people that have nightmare disorder?
To the best of my knowledge through extensive research there are no famous people who have been diagnosed with nightmare disorder.
Macroglobulinemia of Waldenstrom?
DefinitionMacroglobulinemia of Waldenstrom is a cancer of the B lymphocytes (a type of white blood cell). It is associated with the overproduction of proteins called IgM antibodies.Alternative NamesWaldenstrom's macroglobulinemia; Macroglobulinemia - primary; Lymphoplasmacytic lymphomaCauses, incidence, and risk factorsWaldenstrom's macroglobulinemia is a result of a condition called lymphoplasmacytic lymphoma. The cause of the overproduction of the IgM antibody is unknown, but researchers believe it is made by lymphoma cells.Overproduction of IgM causes the blood to become too thick. This is called hyperviscosity. It occasionally makes it harder for blood to flow through small blood vessels.About 1,500 people in the United States are diagnosed with Waldenstrom's macroglobulinemia every year. Most people with this condition are over age 65, however, it may occur in younger people.SymptomsBleeding of the gumsBlurred or decreased visionDizzinessEasy bruising of the skinFatigueHeadacheMental status changesNosebleedsNumbness, tingling, or burning pain in the hands, feet, fingers, toes, ears, or noseRashUnintentional weight lossVision loss in one eyeAdditional symptoms that may be associated with this disease:Bluish skin discolorationFingers that change color upon pressureFlank painSwollen glandsSigns and testsA physical examination may reveal a swollen spleen, liver, and lymph nodes. An eye exam may show enlarged veins in the retina or retinal bleeding (hemorrhages).A CBC shows a low number of red blood cells and platelets. A blood chemistry shows evidence of kidney disease. A serum viscosity test can tell if the blood has become thick. Symptoms usually occur when the blood is four times thicker than normal.A test called serum protein electrophoresis shows an increased amount of the IgM antibody. Levels seen in Waldenstrom's macroglobulinemia are generally greater than 3 g/dL.Bone lesions are very rare. If they are present, a bone marrow examinationwill show cells that resemble both lymphocytes and plasma cells.Additional tests that may be done:24-hour urine proteinTotal proteinSerum globulin electrophoresisImmunofixation in urineT (thymus derived) lymphocyte countTreatmentPlasmapheresis removes unwanted substances from the blood. In macroglobulinemia, it removes or reduces the high level of IgM, and is used to quickly control the symptoms caused by blood thickening.Drug therapy may include steroids, Leukeran, Alkeran, Cytoxan, fludarabine, or rituximab, or combinations of chemotherapy drugs.Patients who have a low number of red or white blood cells or platelets may need transfusions or antibiotics.Expectations (prognosis)The average survival is about 6.5 years. Some people live more than 10 years.In some people, the disorder may produce few symptoms and progress slowly.ComplicationsChanges in mental function, possibly leading to comaCongestive heart failureGastrointestinal bleedingVision problemsCalling your health care providerCall your health care provider if symptoms of this disorder develop.ReferencesTreon SP, Hatjiharissi E, Leleu X, Roccaro A, Merlini G. Waldenstrom Macroglobulinemia/Lymphoplasmacytic Lymphoma. In: Hoffman R, Benz EJ, Shattil SS, et al, eds. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 88.Rajkumar SV, Kyle RA. Plasma cell disorders. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 198.
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