Queen Sobeknefru, or perhaps a first dynasty pharaoh.
Hatshepsut was the first woman to be a ruler of Egypt
Hatsheput i think, she came from Egypt
Cleopatra
Hatshepsut was the first woman to be a ruler of Egypt
queen hatshepsut
If you mean to rule Egypt in her own right, it was probably a queen named Sobekneferu, who ruled way back in the twelfth dynasty.
King Narmer united Upper Egypt and Lower Egypt during his rule in the 1st Dynasty.
Hatshepsut was the woman who ruled as Pharaoh of Egypt between 1473-1458 BC. (Cleopatra was Pharaoh but did not rule as a man)
Nefrititi was the most popular, and if I'm not mistaken, the only woman to ever rule Egypt.
Egypt
Meretseger, wife of Senusret III of the 12th dynasty of the Egyptian middle kingdom is the first known queen of egypt, though clearly she was not actually the first since most/all previous pharoahs of dynasties 1-11 must have had queens.