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Gram-negative bacteria have an outer membrane made of lipopolysaccharide and proteins, which the Gram-positive bacteria are lacking. More multi-drug resistance is being recognized in this class of bacteria than previously, and they are becoming a formidable foe in the environment because of the lack of new antibiotics to treat infections.
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∙ 9y ago
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∙ 13y agoGram - and + bacteria differ in the structure of their cell walls. Some antibioitics are better able to cross cell walls of gram - or +, so their resistance to these antibiotics differ.(This is one reason). Of course some antibiotics affect both equally or neither.
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∙ 12y agoGram (-) bacteria have a wider spectrum of antibiotic resistance than Gram (+) bacteria because the Gram (-) bacteria are able to share genes that confer resistance between themselves. Therefore, even though a particular bacterium has never encountered most antibiotics, it carries genes that can be activated to protect it from the antibiotics.
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∙ 11y agoGram negative bacteria have thick wall, made up of lipids and polysaccharides molecules so bacteria has harder time penetrating the wall. This is why gram negative are more resistance to antibiotics such as penicillin.
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∙ 15y agoBecause the two layers of the cell wall in gram negative cells protect the cytoplasm better than the one layer in gram positive cells.
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∙ 11y agoIdeally agents used for the control of microbes should be gram positive. The gram negatives cells are more resistand therefore making it harder to kill them.
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∙ 10y agoGram negative cells have a impermeable outer membrane
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How do antibiotics work on gram - negative bacteria?
Gram negative bacterial cells have an outer membrane that interferes with antibiotics and drug entry into the cell. The bacteria that are resistant to antibiotics are E. coli, salmonella, shigella, and Yersina. The first three affect the GI tract and the second causes the Black Death. These are resistant to penicillin. So ampicillin and streptomycin are used.
Why gram positive bacteria typically more resistant that gram negative bacteria to antibiotics that disrupt plasma membranes such as polymyxin B?
Polymixin antibiotics interact with the lipopolysaccharide molecule of Gram negative bacteria. This component forms the outer leaflet of the outer membrane. Gram-positive bacteria do not have an outer membrane or lipopolysaccharide and thus polymixin antibiotics are unable to bind to the cell.
Gram negative bacteria are much more resistant to penicillin because?
Peptidoglycan in Gram-negative bacteria is inaccessible to penicillins because penicillin cannot penetrate the Gram-negative outer membrane.
What antibiotics are made with streptomyces griseus?
S. griseus produces antibiotic, streptomycin, and it is useful against gram negative bacteria. Streptomycin and its relatives are considered reserve antibiotics for resistant bacterial strands because they can be neurotoxic and nephrotoxic.
What does gram negative on a serratia marcescens gram stain mean?
Bacteria are gram positive or gram negative. Serratia happens to be a gram negative bacteria. They appear pink on a gram stain. Gram positive bacteria stain to a purple color on a gram stain. We can classify and ID bacteria using their gram stain and shape. Some antibiotics only work on gram negative bacteria and some only work on gram positive bacteria. It helps a doctor know which antibiotic to use.
What type of infection are antibiotics used to fight?
Antibiotics treat bacterial infections (provided the bacteria isn't resistant to the antibiotic). Different antibiotics are required to treat Gram positive and Gram negative bacteria due to their differing structures. They have no effect on viruses.
How do antibiotics work on gram - negative bacteria?
Gram negative bacterial cells have an outer membrane that interferes with antibiotics and drug entry into the cell. The bacteria that are resistant to antibiotics are E. coli, salmonella, shigella, and Yersina. The first three affect the GI tract and the second causes the Black Death. These are resistant to penicillin. So ampicillin and streptomycin are used.
Why gram positive bacteria typically more resistant that gram negative bacteria to antibiotics that disrupt plasma membranes such as polymyxin B?
Polymixin antibiotics interact with the lipopolysaccharide molecule of Gram negative bacteria. This component forms the outer leaflet of the outer membrane. Gram-positive bacteria do not have an outer membrane or lipopolysaccharide and thus polymixin antibiotics are unable to bind to the cell.
What types of bacteria do antibiotics kill?
Gram negative and gram positive bacteria.
Why might a gram-negative infection be harder to treat than gram-positive infection?
In short, it's because they have a membrane around their cell wall that both increases their toxicity, and makes them more resistant to antibiotics. It makes them more resistant because many antibiotics, such as penicillin, work by destroying the cell walls of bacteria. Because they have an extra membrane around their cell walls, gram negative bacteria have extra protection against the antibiotics.
Which Gran Positive or negative which is more serious?
Gram positive bacteria responds to the Gram stain; gram negative bacteria does not. The two bacteria do not respond to the same antibiotics. Right now the most dangerous bacteria is a gram negative bacteria. That could change.
Why is important to distinguish between Gram-positive and Gram-negative bacteria in diagnosing a bacterial infection?
gram- negative and gram- positive bacteria differ in their response to different antibiotics
Gram negative bacteria are much more resistant to penicillin because?
Peptidoglycan in Gram-negative bacteria is inaccessible to penicillins because penicillin cannot penetrate the Gram-negative outer membrane.
Gram negative bacteria tend to be more?
resistant to being killed.
What antibiotics are made with streptomyces griseus?
S. griseus produces antibiotic, streptomycin, and it is useful against gram negative bacteria. Streptomycin and its relatives are considered reserve antibiotics for resistant bacterial strands because they can be neurotoxic and nephrotoxic.
What does gram negative on a serratia marcescens gram stain mean?
Bacteria are gram positive or gram negative. Serratia happens to be a gram negative bacteria. They appear pink on a gram stain. Gram positive bacteria stain to a purple color on a gram stain. We can classify and ID bacteria using their gram stain and shape. Some antibiotics only work on gram negative bacteria and some only work on gram positive bacteria. It helps a doctor know which antibiotic to use.
Can antibiotics lead to septic shock if used to treat gram-positive bacterial infections?
No, but it can if it is gram negative bacteria..
