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Peptidoglycan in Gram-negative bacteria is inaccessible to penicillins because penicillin cannot penetrate the Gram-negative outer membrane.

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Q: Gram negative bacteria are much more resistant to penicillin because?
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Are archaea bacteria resistant to penicillin?

Without fully explaining how the penicillin antibitic works: yes, archaea are resistant to penicillin. This is because they don't have peptidoglycan in their cell wall. Penicillin works by lowering the newly formed peptidoglycan in multiplying bacteria. It also does other things. The reason it works (this is natural penicillin G) only on Gr+ is because the can't get through the GR- cell wall. (I say this because both + and - HAVE peptidoglycan in their cell wall)


Why does penicillin not work on all bacteria?

Penicillin comes from an antibiotic made by one microbe that acts only against certain others. Some microbes are just resistant toward the antibiotic and another will have to be used. At times not enough or a dose that is too weak will prevent the antibiotic from working. Some antibiotics will work only on Gram negative or Gram positive bacteria. Some are broad spectrum and will work on both.It just is that penicillin resistant bacteria are not affected by penicillin. These have mutated and evolved to resist penicillin. These are often called "super bugs".


What would happen if a suspension of bacteria is placed in a distilled water with penicillin?

eventually the bacteria would die because the penicillin would interfere with the ability to synthesize a cell wall thus the bacteria wouldn't divide. and the existing bacterial cell wall would lengthen and become frail. However, the bacteria must be gram-positive because they have cell walls composed of peptidoglycan, which is ideal for penicillin to attack.


Why gram positive bacteria typically more resistant that gram negative bacteria to antibiotics that disrupt plasma membranes such as polymyxin B?

Polymixin antibiotics interact with the lipopolysaccharide molecule of Gram negative bacteria. This component forms the outer leaflet of the outer membrane. Gram-positive bacteria do not have an outer membrane or lipopolysaccharide and thus polymixin antibiotics are unable to bind to the cell.


How might the physical differences between gram positive and gram negative bacterica contribute to differences in chemical resistances?

Gram positive bacteria do not contain a protein sheath over their peptidoglycan membrane layer. Because of this, a gram negative bacteria's membrane (which contains a protein coating over the peptidoglycan) is more resistant to being penetrated by chemicals.

Related questions

Why some bacteria are resistant from penicillin?

Because its bigger and bigger is better ;)


Why is penicillin not as effective as it was fifty years ago?

This isn't entirely true. Penicillin is still as effective against the bacteria that it combated 50 years ago, but new strains of penicillin resistant bacteria have evolved since 50 years ago. This means that penicillin is less effective against a larger percentage of bacteria than it was 50 years ago, solely because of the new, anti-biotic resistant strains. For more information, search Natural Selection.


Are archaea bacteria resistant to penicillin?

Without fully explaining how the penicillin antibitic works: yes, archaea are resistant to penicillin. This is because they don't have peptidoglycan in their cell wall. Penicillin works by lowering the newly formed peptidoglycan in multiplying bacteria. It also does other things. The reason it works (this is natural penicillin G) only on Gr+ is because the can't get through the GR- cell wall. (I say this because both + and - HAVE peptidoglycan in their cell wall)


Why might a gram-negative infection be harder to treat than gram-positive infection?

In short, it's because they have a membrane around their cell wall that both increases their toxicity, and makes them more resistant to antibiotics. It makes them more resistant because many antibiotics, such as penicillin, work by destroying the cell walls of bacteria. Because they have an extra membrane around their cell walls, gram negative bacteria have extra protection against the antibiotics.


Why does penicillin not work on all bacteria?

Penicillin comes from an antibiotic made by one microbe that acts only against certain others. Some microbes are just resistant toward the antibiotic and another will have to be used. At times not enough or a dose that is too weak will prevent the antibiotic from working. Some antibiotics will work only on Gram negative or Gram positive bacteria. Some are broad spectrum and will work on both.It just is that penicillin resistant bacteria are not affected by penicillin. These have mutated and evolved to resist penicillin. These are often called "super bugs".


Can i take amox tr-k clv if im allergic to penicillian?

Yes, amoxicillin is a member of the penicillin group of antibiotics. Yes and No, it is more of the bacteria of penicillin than the actual antibiotic. It is a part of the penicillin family true, and is given to patients that are allergic to penicillin. Not just because the bacteria is penicillin resistant.


Why is penicillin not effective anymore?

Penicillin does still work, just not as well. This is because the few germs that can survive the antibiotic will then pass on that capabaility to their progeny; the basics of genetics in action. This means that later generations of the same bacteria need more to kill them or, even worse, are entirely immune to the effect of penicillin. Some strains of bacteria have evolved to the point that they are not only unaffected by penicillin itself, but all drugs similar to penicillin (beta-lactams). One such strain is MRSA (methicillin-resistant Staphylococcus aureus).


Why do some people become resistant to certain antibiotic?

Antibiotic resistance results from misusing antibiotics. Antibiotics should only be used to treat bacterial infections. Many industrial farmers will give healthy animals a daily dose of low level antibiotics to stimulate growth. These daily doses help to create antibiotic resistant super bugs.


Can humans take animal penicillin?

Penicillin G is made for humans and animals. " Pen Strep" refers to a mixture solution of one part Penicillin and One part streptomycin. It is a standard antibiotic used for a wide range of gram negative and gram positive bacteria in both animals and humans. You wouldn't want to use animal penicillin on a human because animal penicillin often comes in a higher or lower dose dependent on factors such as weight and lbs per milligram rules. As with any Antibiotic drug....You could overdose and cause serious injury and possibly death. You could under dose which could lead the bacteria to become resistant to the antibiotic which in case, would only lead to the need of another antibiotic to cure the infection.


How many lives penicillin saved?

147,874,294,765 isn't it great


Why are gram positive bacteria more heat resistant than gram negative bacteria?

Gram positive bacteria contain more peptidoglycan than gram negative bacteria which is the substance responsible for the increased strength of gram positive bacterias cell walls therefore making them more resistant to heat. Gram negative do contain peptidoglycan but much, much less


What would happen if a suspension of bacteria is placed in a distilled water with penicillin?

eventually the bacteria would die because the penicillin would interfere with the ability to synthesize a cell wall thus the bacteria wouldn't divide. and the existing bacterial cell wall would lengthen and become frail. However, the bacteria must be gram-positive because they have cell walls composed of peptidoglycan, which is ideal for penicillin to attack.