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Leucovorin (folinic acid) is administered to the patient several hours after the methotrexate (MTX). The rationale is that the MTX selectively kills malignant cells while normal cells are rescued by leucovorin (folinic acid). (Golan,Principles of Pharmacology,third ed.,pg 577)
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What is leucovorin typically used for?
Leucovorin is typically used as a rescue medication to reduce the toxic effects of high-dose methotrexate chemotherapy. It helps protect healthy cells in the body from the harmful effects of methotrexate by acting as a "rescue" folate supplement. It is also used in the treatment of anemia caused by folate deficiency.
What drugs are used as a RESCUE from toxicity of methotrexate?
When you are on methatrexate it tends to deplete the folic acid in your body which can be bad for the kidney. I myself take 10 mg of MTX once a week to help stop inflammation that is the result of Rheumatoid arthritis's. to build up the folic acid I take 5mg of Megafol Folic acid every day. In any case you should speak to your doctor as Methatrexate can be a dangerous drug if there are any problems.
Can you take methotrexate and champix together?
yes
Can you take methotrexate and guaifenesin together?
yes
Can a dog take methotrexate?
Yes, sometimes vets do give methotrexate, but it is in combination with other medications, and usually in extreme cases. If you have human methotrexate, do not attempt to dose it to your dog. This should only be done under vet care. Methotrexate is fatal if not given correctly.
Can you take methotrexate and methocarbamol together?
You can. There is no interaction between these drugs.
Can you take l-arginine and methotrexate together?
Ask your doctor.
How long does leucovorin infuse over?
one hour
Can you take Ativan and methotrexate at the same time?
There have been reports of people taking Atvian and methotrexate together at the same time. However taking both of these drugs together can increase the risk of side effects such as dizziness and drowsiness.
Is it safe to take Ambien CR and Methotrexate?
There are no known interactions between Ambien CR and methotrexate. It is advisable to make sure your doctor has a full list of all the medications you are on, even if they were given to you by other doctors.
What color for methotrexate?
Methotrexate is usually yellow.
Can you take statin when taking methotrexate?
Methotrexate when taking with atorvastatin (Lipitor), pravastatin (Pravachol), and simvastatin (Zocor), can cause serious liver problems. It's best to consult with a physician or pharmacist before taking these two together.
