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Q: Why are males affected more often than females by succinct genetic disorders. Use a Punnett square to explain?
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Using a punnett Square explain why males are affected more often than females by sex linked genetic disorders?

This is a very short compared to the X chromosome with which it is pair. In X-linked genetic disorders (such as Duchenne's muscular dystrophy}. In the x an y type of sex determinate organisms, the genes affecting the expression are only located on X-chromosome, the y chromosome does not have its contrasting allelic gene. Hence, when a female organism has a recessive gene(for example colorblindness), its another X chromosome obtained from male gamete will mask the expression, and the female will escape color blindness. In case of male, the x-chromosome carrying a gene for colorblindness from its mother will have its expression because its counterpart (y-chromosome) does not carry its allelic form. Hence although the genes cause defects are carried by females, the males are affected more. This can be explained by drawing a Punnett Square for male and female gametic fusion possibilities.


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