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Why do Males tend to be affected in greater numbers by X-linked recessive genetic disorders than females?
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∙ 13y ago
males have only one X chromosomes
Juliet Olson
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∙ 14y agoIn humans males sex is determined by the presence of the Y chromosome. This is a very short compared to the X chromosome with which it is pair. Therefore if there is a genetic defect on the X chromosome then it cannot be masked by a beneficial one on the Y as it is simply not there.
Wiki User
∙ 13y agoX linked recessive disorders are most commonly found in males as males have an X and a Y chromosome (XY) whereas females have XX. This means that if a female contains one of the recessive genes (Xx) they remain unaffected by the condition as they still have the dominant normal gene, males on the other hand only have one x chromosome so are more liable to get the disorder.
A female who is unaffected by the disorder but has the recessive gene (Xx) is called a carrier and could potentially pass on the disorder to her offspring.
Wiki User
∙ 12y agoMales are more often affected by x linked disorders because the y chromosome offers less genetic protection from much of the genetic material passed from the mother to the male offspring.
I you imagine the Xy combination more like a capital X and a lower case y for relative size you can better visualize the difference in genetic material contained on the y vs. X chromosomes (this is illustrative only). If the negative genetic trait is passed on from the mother to the son on the part of the X chromosome that has no corresponding allele on the y from the father the genetic disorder will manifest in the son.
If the father does not have the characteristic and the mother is a carrier, she will pass her affected X chromosome to 50% of her daughters but all will be carriers and not be affected by the recessive disorder due to the presence of the fathers X chromosome.
50% of her sons will have the disorder and 50% will not have the recessive allele.
Wiki User
∙ 10y agofemales may mask recessive genes with dominant genes for the disorder.
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∙ 13y agoBecause females have two dominant genes for the disorder
Wiki User
∙ 11y agomales have only one X chromosomes
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How do you recognize a pedigree for an x-linked recessive allele in human beings?
For a recessive sex-linked trait to manifest in women it would have to be in double dose (XaXa) while for men in single dose (XaY). Women carriers would have one of each but would not be affected (XAXa). Knowing this it's quite easy to spot pedigrees where this kind of inheritance occures.Heterozygote mothers (gene carrier) can have sons that are affected (50% chance);Affected mothers have only affected sons (100%);No first generation daughter of an heterozygote mother will be affected but there is a 50% chance that she is a carrier;Affected fathers with normal mothers will have zero sons that are affected but all their daughters will be carriers;
Why can females but not males be carriers of sexlinked genetic disorders?
Several genetic disorders are caused by genes on the X chromosomes.
Colorblindness is more common in males than in females because?
the allele for colorblindness is recessive and located on the X chromosomes
A dominant x linked trait would be more common in males or females?
If the trait is recessive and on the male chromosome (Y), then it is impossible for females to get it since they do not possess a Y chromosome. If you meant a recessive sex-linked trait on the X chromosome (like male pattern baldness), then males are still more likely to get it since they only receive one X chromosome and if it is affected they would automatically have the trait (whereas females have 2 copies and would only have the trait if both parents passed on chromosomes containing the recessive allele.) Females can be carriers, though. If they are a carrier (have one affected X chromosome) for the trait then their male children would have a 50% chance of inheriting the trait and their female children would have a 50% chance of becoming carriers.
Why are female carriers?
Females carry two X chromosomes; males only carry one. A female carrier carries a defective recessive allele for a gene on the X chromosome. Thus, the female will not be affected because she still has a copy of the dominant allele. However, if she has any male children, that child will be affected because males inherit their X chromosome from their mothers.
What form of Niemann Pick can be inherited?
All forms of NPD are inherited autosomal recessive disorders, requiring the presence of an inherited genetic mutation in only one copy of the gene responsible for the disease. Both males and females are affected equally.
Why are males often affected more than females by sex-linked genetic disorders?
males have only one X chromosomes
What evidence is there that the long and round did not become blended?
A number of genetic disorders are caused when an individual inherits two recessive alleles for a single-gene trait. Recessive genetic disorders include Albinism, Cystic Fibrosis, Galactosemia, Phenylketonuria (PKU), and Tay-Sachs Disease. Other disorders are also due to recessive alleles, but because the gene locus is located on the X chromosome, so that males have only one copy (that is, they are hemizygous), they are more frequent in males than in females.
What evidence is there that the long round allels did not become blended?
A number of genetic disorders are caused when an individual inherits two recessive alleles for a single-gene trait. Recessive genetic disorders include Albinism, Cystic Fibrosis, Galactosemia, Phenylketonuria (PKU), and Tay-Sachs Disease. Other disorders are also due to recessive alleles, but because the gene locus is located on the X chromosome, so that males have only one copy (that is, they are hemizygous), they are more frequent in males than in females.
What evidence is there that the long and round alleles did not become blended?
A number of genetic disorders are caused when an individual inherits two recessive alleles for a single-gene trait. Recessive genetic disorders include Albinism, Cystic Fibrosis, Galactosemia, Phenylketonuria (PKU), and Tay-Sachs Disease. Other disorders are also due to recessive alleles, but because the gene locus is located on the X chromosome, so that males have only one copy (that is, they are hemizygous), they are more frequent in males than in females.
Which race has more problems with eating disorders?
Caucasian females between the ages of 15 and 26. However, all races and age groups are affected.
Who can be carrier of autosomal disorder?
females
Assume that a particular genetic condition in a mammalian species causes an inability to digest starch This disorder occurs with equal frequency in males and females in most cases neither parent is af?
This genetic condition is likely an autosomal recessive trait since it occurs with equal frequency in males and females. If neither parent is affected, it suggests that both parents are carriers of the condition. In order for a child to be affected, they would need to inherit two copies of the recessive allele, one from each carrier parent.
Why do men have more sex-linked disorders than women?
If you are a carrier of a sex-linked genetic disorder, you will carry that disorder based on your sex hormones, because they influence the appearance of the trait. A person who carries the trait will have the disease but may not show it. ---- Sex-linked disorders are genetic disorders linked directly to a human's chromosomes. In the case of chromosomes, females (XX) give an X chromosome to their offspring. Males (XY) can give either an X or a Y chromosome to their offspring. Because only males can have a Y chromosome, sex-linked disorders usually occur in males.
A recessive gene located on the X chromosome is the cause of hemophilia in affected individuals. Males are more likely to have hemophilia than females because?
Males only have one copy of the X chromosome
Is gender important for a eating disorder?
About 90% of eating disorders affect females.
Why are sex linked recessive disorders such as hemophilia most often seen in males and rarely seen in females?
The recessive genes are present on the X-chromosome. Female chromosome has another X-chromosome, which is dominant and masks the defective gene, and it is quite rare that both the chromosomes have recessive alleles. But, in males, the Y-chromosome has nothing to over mask the defective gene and the abnormality shows up in the form of the disease.
