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aspirin blocks the COX-1 pathway, which helps for antiinflammatory purposes, but if you block this pathway, then all the arachidonic acid that begins that pathway gets diverted to the the leukotriene synthesis pathway via the enzyme lipooxygenase... which causes bronchoconstriction.

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10y ago
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11y ago

not recommended to take Aspirin for asthmatic patient and for children.

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Q: Why asthmatic patients is a contraindication for aspirin?
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