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Because Clindamycin kills the bacteria in your stomach (the good bacteria that helps digest food) and laying down will cause GERD/really bad heartburn. It is better to stay upright or sitting up so this doesn't happen.

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12y ago
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9y ago

You are not supposed to lie down for 10 minutes after taking Clindamycin because it can irritate the esophagus. You should give the pill plenty of time to dissolve in the stomach before laying down.

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Q: Why can't I lie down for 30 minutes after taking a clindamycin?
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