Patients with Marfan sometimes develop dental problems related to crowding of the teeth caused by a high-arched palate. They can also develop overgrowth and inflammation of the gums, due to those being part of our connective tissue.
This condition is much more prevalent in patients with Marfan syndrome than in the general population.
Myopia (nearsightedness). Most patients with Marfan develop nearsightedness, usually in childhood.
Males with Lesch-Nyhan syndrome develop neurologic problems during infancy. Infants with Lesch-Nyhan syndrome have weak muscle tone (hypotonia) and are unable to develop normally.
About 90% of Marfan patients will develop cardiac complications.
Most patients recover in three to four months, but about 50% have recurrences for several years. Some patients develop complications
constipation
Many patients with SS also develop a variety of skin problems that include dry patches, vasculitis, and cutaneous B-cell lymphoma. These and other dermatologic disorders are more common in SS than was previously thought.
Between 50 and 80% of Marfan patients have dislocated lenses.
Patients who develop Lambert-Eaton myasthenic syndrome should be thoroughly screened for the presence of a previously undetected cancer
Lesch-Nyhan syndrome is a rare genetic disorder that affects males. Males with this syndrome develop physical handicaps, mental retardation , and kidney problems.
Marfan patients may develop kyphosis either in the upper (thoracic) spine or the lower (lumbar) spine.
Some patients with Marfan develop cystic disease of the lungs or recurrent spontaneous pneumothorax, which is a condition in which air accumulates in the space around the lungs. Many will also eventually develop emphysema.