• 
• 1 answer

It is estimated that one person in every 3000-5000 has Marfan syndrome, or about 50,000 people in the United States.

• 
• 1 answer

• 
• 1 answer

• 
• 1 answer

1:97

• 
• 1 answer

Between 50 and 80% of Marfan patients have dislocated lenses.

• 
• 1 answer

People with Marfan syndome have problems with their eyes, heart, skeleton, and people with it are usually very tall and skinny

• 
• 1 answer

Recent advances in Marfan syndrome treatment have prolonged the life expectancy of patients considerably. Changes in how the syndrome is treated, including medication, surgical interventions, and monitoring for complications of the syndrome (eg, aneurysms), are all responsible for the increase in life expectancy. The prolongation in life expectancy can be seen by taking a look at statistics from 1972, in which the life expectancy was 32 years, and from 1996, where patients with Marfan syndrome had a life expectancy of 61 years.

• 
• 2 answers

Marfan syndrome is an autosomal dominant condition caused by a genetic mutation. The mutation occurs on chromosome 15 and affects the gene that encodes a protein called fibrillin-1. Over 100 mutations have been described, all of which impair the function of fibrillin-1.

The precise reasons for the mutations are unknown. How the mutation manifests as the Marfan syndrome is also uncertain. There is mounting evidence that the fibrillin-1 defect allows for unabated activity of transforming growth factor-beta (TGF-beta), which causes the clinical manifestations of the syndrome (eg, hyperextensible joints, arachnodactyly, dislocation of the lens, aortic aneurysm).

Because the condition is inherited in an autosomal dominant pattern, a parent with Marfan syndrome has a 50% chance of passing the defective gene on to his/her offspring.

Some diseases are also associated with features that resemble Marfan syndrome. For example, multiple endocrine neoplasia (MEN) type III is associated with what's been called a marfanoid habitus -- patients commonly have the elongated axial bones and hyperextensible joints seen in true Marfan syndrome. MEN-III is caused by a mutation in the RET gene on chromosome 10. It is inherited in an autosomal dominant pattern.

• 
• 1 answer

It is presently not useful as a diagnostic test because there is evidence that there can be mutations in the fibrillin gene that do not produce Marfan.

• 
• 1 answer

Marfan syndrome can result in sudden death due to increased risk for aortic dissection or aneurysm when undiagnosed or untreated. If diagnosed and managed early, patients can have a normal life expectancy.

• 
• 1 answer

Marfan syndrome is an autosomal dominant disorder. An affected person has a 50% chance of passing it on to each offspring, regardless of gender.

• 
• 1 answer

Yes you can catch it in many ways

• 
• 2 answers

Yes

• 
• 1 answer

People affected with Marfan's typically have long bones that are longer than normal (i.e. longer than normal legs and arms), longer than normal fingers, joints that are naturally more flexible than the average person. They can also have problems with their heart, aortic artery, and eyes.

• 
• 1 answer

The "autosomal dominant" method of inheritance.

if your question as

Marfan syndrome is the result of inheriting a single allele. Individuals with Marfan syndrome are tall and long-limbed, and have both cardiovascular and eye defects. The inheritance of Marfan syndrome is an example of ______.

then the answer is pleiotropy

• 
• 1 answer

When you are born, because it's genetic.

• 
• 1 answer

No, it's not terminal in itself, but if the heart and aorta are not monitored properly, then there is a chance of sudden death by aortic dissection (the aorta tearing). So, it is definitely life-threatining. Therefore, someone with Marfan syndrome needs an echocardiogram, MRI, CT scan, or TEE of their entire aorta at least once a year to check for aneurysms and monitor their growth. If the aorta is growing rapidly or the valves are leaking a lot, more frequent monitoring is advised. Taking a medication to lower the blood pressure, like beta blockers. Preventative aortic surgery also extends the life expectancy. With proper monitoring, people with Marfan syndrome have an average lfe expectancy.

• 
• 1 answer

Pleiotropy.

• 
• 1 answer

Yes he had bot he never did outing of it

• 
• 1 answer

Marfan syndrome is sometimes called arachnodactyly, which means "spider-like fingers" in Greek, since one of the characteristic signs of the disease is disproportionately long fingers and toes.

• 
• 1 answer

Abraham Lincoln

• 
• 2 answers

About 1 in 5,000 people have Marfan syndrome, including men and women of all races and ethnic groups. About 3 out of 4 people with Marfan syndrome inherit it, meaning they get the genetic mutation from a parent who has it. But some people with Marfan syndrome are the first in their family to have it; when this happens it is called a spontaneous mutation. There is a 50 percent chance that a person with Marfan syndrome will pass along the genetic mutation each time they have a child.

• 
• 1 answer

No, Marfan Syndrome is an inherited disorder of connective tissue. It is not an infectious disease.

• 
• 1 answer

Abraham Lincoln had it and Michael Phelps still has it. do any supermodels have mar fans syndrome

• 
• 1 answer