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Dennie-Marfan syndrome is characterized by specific symptoms including the presence of periorbital edema, which leads to prominent lower eyelid folds, and a tendency to develop eczema. Individuals may also exhibit other features such as dry skin, Allergies, and Asthma. Additionally, they might have skeletal abnormalities like arachnodactyly or scoliosis. The condition is associated with a genetic mutation affecting connective tissue.

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