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Actually the pH of the stomach very acid relative to pH 7 (between pH 1-4). An acidic stomach is optimal for the breaking of hydrogen bonds that makes up the complex compounds in the food we ingest, like proteins. The acidity of the stomach is generated by the excretion of hydrochloric acid (HCl) which combines with pepsinogen to create pepsin into the stomach, which is a strong acid.
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∙ 15y ago
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Which organ secrets enzymes that are active at a low pH?
The stomach secretes protease enzymes that work best at a pH of around 2.
What PH would work for enzymes produced in the stomach?
It's about 7.5, which means that it is slightly basic. The stomach is acidic, so not only does the basic pH of the small intestine allow the enzymes to function, but it also counteracts with the acidity of the stomach.
Can enzymes work over a broad range of PH levels?
Most enzymes work best at a certain pH, however there are some enzymes that can operate over a broad pH range.
Why does the stomach contain HCl?
HCl lowers the pH in the stomach and provides the acidic conditions for the digestive enzymes in the stomach to work effectively.
Can enzymes function at any pH?
No. They function best at the pH corresponding to their usual/intended environment. For example, pepsin, present in the stomach, which is highly acidic, functions best at acidic pH, while trypsin, secreted into the duodenum together with basic bicarbonate, functions best at moderately basic pH. This is true also within subcellular compartments: the optimal pH of lysosomal enzymes is acidic, matching the acidic proteolytic environment inside the lysosome. That said, most enzymes present in the cytosol (~neutral) and blood (~neutral) function best around neutral pH.
What factors affect the activity of enzymes?
Enzymes work best in the pH and temperature that they are " designed " for. A pepsin enzyme works best in the low pH environment of the stomach, while amylase works best at mouth temperature and ~ 7 pH. Heat and out of range pH can denature enzymes and not only affect their activity but inactivate them.
What pH does amylase works best with?
Most human enzymes work at a optimal pH of 7.4, but other enzymes work at many different pH ranges, for example Pepsin works best at an optimal pH of 2.6 and Trypsin works best at an optimal pH of 7.8.
Does digestive enzymes will still function in the small intestin?
The small intestine is the site of work of some digestive enzymes that are secreted there. It is not an ideal site for the continued work of enzymes from the stomach, as the pH is not hospitable for the work of those gastric enzymes.
What is the acid secreated by the stomach?
Hydochloric acid is produced in the stomach to a) kill pathogens in our food b) gives optimum pH for enzymes to work in
Why do different enzymes have different optimum pH?
Enzymes only work best at a certain pH. This is called an optimum pH for that enzyme. An example is the enzymes found in the stomach. The pH found there is very acidic (around pH2). If this same enzyme was in another part of the body it would either not work well or maybe not at all.The proper pH keeps the protein shape of the enzyme. Anything above or below that can stop it or even denature it. When it is denatured, it will loose the shape it has to be in to work. If you have a screw you need to remove from something, the proper screwdriver is necessary or you will strip the head (damage) the screw.
Do enzymes work best at a narrow PH range?
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What is the benefit of stomach acid?
There are many benefits to Stomach Acid. One of the reasons is that some of the Enzymes that work in the stomach work best at the pH of 2 which is similar to the pH of Stomach acid which is Hydrochloric Acid (HCl). This makes the process of Digestion go much faster. Another benefit is that the Hydrochloric Acid along with the Muscle Contraction in the Stomach helps break down any bones you eat and turns all the food into mushy smaller pieces which then goes to the Small Intestine where it can be broken down by other Enzymes and then sucked into the bloodstream.
