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Dogs are weak at an early age because they mature (grow) to full size in a short period of time. I would estimate most dogs reach adult size within 1-yr. This rapid growth consumes a great deal of resources. This is coupled with an immune system that is immature.

I might also add that many of your larger breeds of dogs have weaker immune systems than many of the smaller breeds, again, because they have to grow to a much larger size in such a short period of time.

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Q: Why do puppies get weak in 2 months old?
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