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Direct Coombs or direct Antiglobin (DAT)
for dignosis of HDN case
ANA or Antinuclear Antibody is a test that helps detect autoimmune disorders in the body. This is usually done to diagnose systemic lupus erythematosus or SLE.
An indirect Coombs' test looks for antibodies to someone else's red blood cells in the patient's serum
The DIF (direct immunofluorescence) test on a skin biopsy involves staining the tissue sample with fluorescently labeled antibodies to detect the presence and localization of specific proteins (such as antibodies or immune complexes) in the skin. This test helps in diagnosing autoimmune skin conditions such as pemphigus vulgaris, bullous pemphigoid, and lupus erythematosus.
Certain HLA types have been linked to diseases, such as rheumatoid arthritis, multiple sclerosis, serum lupus erythematosus, and other autoimmune disorders.
http://wiki.answers.com/Q/What_is_an_anti_nuclear_ab_blood_test"
There is no single definitive test for diagnosing lupus. A diagnosis is based on symptoms, history, a variety of tests, and process of elimination. Because of this subjective component, it is possibly to be wrongly diagnosed. A good rheumatologist will work hard and carefully to be sure the diagnosis is correct.
There are over 100 autoantibodies that can be found in lupus patients. Not all lupus patients have the same autoantibodies. The most common tests are antinuclear antibody with immunofluorescence (ANA), anti double stranded DNA, anti Snith, anti Ro, anti La, and anti SSA.
Coombs Test
lupus is a complicated disease that can most defiantly effect everybody. you cant get rid of lupus with medication so you have to really avoid this. you have to ask you doctor to test for lupus.
Systemic lupus erythematosus (SLE or lupus) is a chronic autoimmune disease that is potentially debilitating and sometimes fatal as the immune system attacks the body's cells and tissue, resulting in inflammation and tissue damage. SLE can affect any part of the body, but most often harms the heart, joints, skin, lungs, blood vessels, liver, kidneys and nervous system. The course of the disease is unpredictable, with periods of illness (called flares) alternating with remission. Lupus can occur at any age, and is most common in women, particularly of non-European descent. Lupus is treatable symptomatically, mainly with corticosteroids and immunosuppressants, though there is currently no cure.== == The word itself is also Latin for Wolf