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Answer I'VE BEEN TAKING METFORMIN FOR ALMOST A YEAR AND BOY I TELL YOU IT HAD CHARLIE HORSE IN MY LEGGS MANY OF TIME AND MY DR. INCREASE THE DOSE I HAD A MUSCLE SPASM IN THIGHS USALLY IT STOP AFTER THE BODY ADJUST TO ITAnswer

I've been taking metformin for 12 years and I can't say that I've noticed any muscle spasims from using it, but then again no two people react the same way to meds. You would be far better off asking your doctor or your pharmist and see what they have to say as the metformin might not be your problem at all.

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Q: Why do you have a increase in muscle spasms when you take metformin?
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