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You get hives from a medication because you are allergic to it. A more serious allergic reaction would be to have your throat swell so you can't breathe. That's why you don't use any product you find you are allergic to.

These are considered severe allergic reactions: rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue.

You can also have irritation at the application site.

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Q: Why does benzocaine give you hives?
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