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When acid is added to the reaction mixture after refluxing, the amino group is protonated, making it soluble in water. When the Na2CO3 is added, the proton is removed and the benzocaine is no longer soluble. Thus it begins to precipitate out of solution when the reaction mixture is neutralized.

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Q: Why does benzocaine precipitate during neutralization?
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Related questions

What is the chemical reaction for neutralization?

acid+alkali=salt+wateracid+base=precipitate+waterPrecipitate is an insoluble salt


How do you know when an insoluble salt is formed by an acid base neutralization?

Generally it will precipitate out of solution so you can see it.


What is the difference between neutralization titrations and precipitation titrations?

A precipitation titration involve (the name is clear) the formation of a precipitate.


In what reaction an acid and a base produce a salt and a water?

Called an 'acid base' reaction or a 'proton transfer' reaction.Only when a precipitate (of an insoluble salt) is formed, it is called a 'salt formation' reaction.


A hydronium ion reacts with a hydroxide during solution solvent neutralization?

No. It reacts during an acid-base neutralization.


Does A hydronium ion reacts with a hydroxide during solvent solvent neutralization?

No. It reacts during an acid-base neutralization.


Does a hydronium ion react with a hydroxide ion during solute-solvent neutralization?

No. It reacts during an acid-base neutralization.


A solid that forms out of a solution?

Precipitate is a solid formed from a solution during a chemical reaction.


Why does the temperature increase and decrease during neutralization?

Neutralization is an exothermic chemical reaction and thus heat is given out.


Is benzocaine an amide based anesthetic?

No, benzocaine is an ester.


What do you call a solid that forms during a chemical reaction when solutions are mixed?

precipitate


What is a benzocaine?

A benzocaine is a local anaesthetic used as a topical pain reliever.