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HDN only occurs in rhesus negative women who have been sensitized by positive blood.

Rhesus positive mother can have a rhesus negative baby.

In rhesus positive group, they have the antigen Rh. When this antigen from baby enters mother's blood circulation, because of inutero bleed in pregnancy; mother's blood cells will react to the foreign antigen and produce antibodies which are harmful to the baby's blood cells when they cross the placenta and enter baby's blood stream. These antibodies will break baby's blood cells down causing haemolytic disease.

Whereas in rhesus positive mother with negative baby, if baby's blood enters mother's circultaion it will not produce any antibodies as there are no antigens in Rh negative blood. And if mother's blood mixes with baby's blood in the womb, baby will not have the ability to produce antibodies as their immune system is not developed. So there is no chance for haemolytic disease.

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Q: Why does haemolytic disease of the newborn not occur in rhesus positive mothers with a rhesus negative baby?
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Related questions

What blood group should the father have if the mothers A Positive and the Baby's A negative?

A-


Can a rhesus negative mother with antibodies in her bloodstream go on to have a normal healthy baby?

Erythroblastosis Fetalis is a disease that affects mothers with a positive RH factor when their unborn babies have a negative RH factor. It only has negative side-effects during the second pregnancy.


If the mothers blood type is o positive and the sons blood type is o negative what types can the dad be?

Only AB negative.


If the mother has type O positive blood what type of blood type does the father have to be to have a baby?

The father can have any variety of blood type. The only rare complication could occur if the father had A or B group blood, where after birth the mothers immune system attacks the babies red blood cells if it is either A or B. However, this is rare and not usually serious. You may be concerned about "Haemolytic disease of the Newborn" this mainly happens in Rheus D Negative mothers i.e. blood types A, B, AB or O negative if the baby is Rhesus D positive e.g. O positive. Plus the mother must have previously been exposed to Rhesus D positive blood e.g. previous chilbirth. But in this day and age it is very uncommon as it can be prevented both before and after birth. So you can have a baby no matter what blood type the father is.


IF a mother is HR negative and father is HR positive why is second pregnancy a problem?

If the mother is Rh negative and the father Rh positive there is a possibility that the unborn baby will be Rh positive as well. If the baby is Rh positive than the mother (who is Rh negative) has antibodies made for Rh positive substances which would include the baby. Basically the mothers body will attack the baby because it is not a match with her body. Commonly this is not as much of a problem with the first baby because the body does not build up the resistance to the first child but the second child will often run into complications because the body has built up antibodies against the second child's Rh positive blood. This is often called Rhesus disease or Rh disease.


When should an Rh-positive mother should be concern about erythroblastosis fetalis?

This usually occurs with Rh-negative mothers carrying Rh-positive children. Ask your doctor.


What kind of serious problems can happen if the Rh-negative pregnant mothers blood cells start to attack the Rh-positive babies blood cells?

If the antibodies in Rh negative pregnant mothers attack the blood cells of an Rh positive baby, the baby may be damaged by a low blood cell count. This hemolytic anemia can be prevented by the use of Rhogam in each pregnancy in an Rh negative mother.


What kind of serious problems can happen if the Rh-negative mothers blood cells start to attack the Rh-positive babies blood cells?

If the antibodies in Rh negative pregnant mothers attack the blood cells of an Rh positive baby, the baby may be damaged by a low blood cell count. This hemolytic anemia can be prevented by the use of Rhogam in each pregnancy in an Rh negative mother.


What happens if mother is rh positive and father is rh negative?

The rhogam shot is routinely given to mothers who are rh negative who may have rh positive babies. If you are rh positive there is no need to get the shot. However, if you are rh positive and get the shot it will not effect you or the baby.


How many infants whose mothers have fifth disease are born with signs of the disease?

About one-third of infants whose mothers contract fifth disease during pregnancy show signs of infection at birth.


Why the child is immune to the disease that the mothers have?

The child isn't.


How did Saint Lucy cure her mothers disease?

By praying for her.